Search PubMedSearch

Biomedical subjects

M A Samsonov

Publications and source records attributed to M A Samsonov.

At least 19 recordsLinked to original sources

[Psychoemotional condition and autonomic nervous system in patients suffering from myocardial infarction in the young age].

The analysis of clinical pattern, psychovegetative disturbances and metabolic defects in coronary patients with a history of myocardial infarction at young age provided information for recognition of two subgroups: normal-weight and overweight patients. Metabolic derangement manifesting with high total cholesterol and triglycerides levels occurred in group II whereas dystonia was registered in both groups as shown by assessment of reactivity and vegetative tone. Background parasympathetic activation and sympathoadrenal activation in exercise grew. Overweight patients seemed to have a marked vegetative dysfunction. The two patterns established have both theoretical and practical significance in terms of design of therapeutical measures.

Autonomic Nervous System

[Characteristics of water-electrolyte balance in patients with labile essential hypertension and various approaches to the optimal therapy with diuretics and low-sodium diet].

A study of 56 males, aged 22 to 56 years, with uncomplicated essential hypertension, stages IB-IIA, where pretreatment examination was followed by repeat investigation after 4 or 5 weeks of treatment with diuretics or low-sodium diets with strict (less than 2 g), moderate (up to 3 g), or mild (4-4.5 g) restriction of sodium uptake, demonstrated a tendency to sodium retention with fluid redistribution from the interstitium to intravascular space in the presence of diuretic treatment. Where dietary sodium was reduced, extracellular sodium was increased owing to increased residual sodium, while total metabolic sodium dropped, and extracellular fluid increased owing to the increase in interstitial fluid. All three variants of the low-sodium diet produced changes in sodium metabolism, with a drop in systemic residual sodium and arterial blood pressure. It is proposed to use strict limitation of dietary sodium for a limited period of time, to be followed by a transition to mildly limited sodium uptake after arterial BP is brought down and stabilized.

Adult

[Nutrition factor in the treatment and prevention of ischemic heart disease under ambulatory care].

Study of the influence of a long-term staged use of diet therapy during prophylactic medical observation of post-myocardial infarction patients has shown that the anti-sclerosis diet used under clinical conditions was effective for relieving the angina pectoris syndrome and obtaining favourable dynamic changes in a number of metabolic parameters. Among the out-patients the diet was used by only 76 per cent. A comparative study of the results of diet therapy during the 3-year medical observation has shown a clear tendency to a gradual reduction of hyperlipoproteinemia and excessive body weight in patients who adhered to the diet. The parameters under study in the group of patients who violated the diet returned to the original level. The incidence of recurrent myocardial infarctions in patients on a diet was twice as low as in those who violated it. Prolonged diet therapy considerably improved parameters of IHD patients' working capacity. A special model has been elaborated for adequate use of the nutritional factor at all stages of the rehabilitation program.

Adult