Search PubMed⌕ Search

Biomedical subjects

M A Perez

Publications and source records attributed to M A Perez.

23 records · Page 2Linked to original sources
PubMed1984

Effect of salicylate on normal and digoxin-intoxicated isolated rabbit heart.

The action of sodium salicylate on normal and digoxin-intoxicated rabbit heart was studied by the Langendorff perfusion method. The drug depressed heart rate, atrioventricular (AV) conduction and contraction force in the normal heart, and reversibly blocked the ventricular pacemakers induced by digoxin intoxication, whereas its effect on sinoatrial frequency as well as AV conduction was potentiated by digoxin. All the effects of sodium salicylate were stronger at pH 7.0 and weaker at pH 7.4, when compared to those at pH 7.2.

Animals↗
PubMedDate not supplied

Patterns of helminth infection and relationship to BCG vaccination in Karonga District, northern Malawi.

Surveys of enteric and urinary helminth infections were carried out in 1999 among 501 schoolchildren and among 320 adolescents and young adults participating in a study of immune responses to BCG vaccine in Karonga District, northern Malawi. Hookworm, Schistosoma mansoni and S. haematobium infections were detected in 64%, 27% and 20% of schoolchildren and in 55%, 40% and 25% of the immunology study subjects, respectively. Other helminths were appreciably less common. The prevalence of 'at least one' helminth infection was 76% among schoolchildren, ranging from 60% to 92% in the 4 schools, and was 79% in the immunology study participants. There was no evidence for an association between the presence of a BCG scar and presence or intensity of infection with worms in the schoolchildren, nor evidence that BCG vaccination of adolescents and young adults had any effect on the prevalence of helminth infections 1 year later.

Adolescent↗
PubMedDate not supplied

Exercise during pregnancy and type of delivery in nulliparae.

OBJECTIVE: To assess the association between participation in aerobic exercise during the first two trimesters of pregnancy and type of delivery in nulliparous women. DESIGN: Nonexperimental, retrospective. SETTING: A large metropolitan area in the southwestern United States. PARTICIPANTS: 137 nulliparous women. OUTCOME MEASURES: Method of delivery. RESULTS: An unadjusted odds ratio showed that sedentary women (n = 93) were 2.05 times more likely to deliver via cesarean section than active women (n = 44), but this relationship was not statistically significant. Through logistic regression analysis with control for the mother's prepregnancy exercise program, age, use of epidural anesthesia, change in prepregnancy to delivery body mass index, labor length, whether labor was induced, and the hospital of birth, the odds of cesarean delivery were found to be 4.5 times greater for sedentary women than for active women. CONCLUSION: Regular participation in physical activity during the first two trimesters of pregnancy may be associated with reduced risk for cesarean delivery in nulliparous women.

Adult↗