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Biomedical subjects

M A Lewis

Publications and source records attributed to M A Lewis.

At least 253 records · Page 14Linked to original sources

Isolation and characterization of two new herpes-like viruses from capuchin monkeys.

Two herpes-like viruses were isolated from capuchin monkey (Cebus apella) brain and (Cebus albifrons) spleen cell cultures, respectively. Both isolates induced similar cytopathic effects consisting of rounded and ballooned cells in the original monkey cell cultures and in a wide range of permissive cell types. Neutralizing antibody to each virus was present in serum from the capuchin monkey from which it was isolated, but the two viruses did not cross-react by neutralization. Fluorescein isothiocyanate conjugates of hyperimmune rabbit serum to one of the isolates showed an antigenic cross relationship between the two isolates. By electron microscopy, herpes-like virus particles were observed in the nucleus and cytoplasm of infected human diploid fibroblast cell cultures. Virus-infected cell cultures stained with acridine orange revealed small deoxyribonucleic acid-containing intranuclear inclusion bodies. Both viruses were inhibited by 5-fluorodeoxyuridine and inactivated by chloroform or exposure to 56 degrees C for 30 min. Antisera prepared against 16 prototype herpesviruses and cytomegaloviruses did not neutralize approximately 100 50% tissue culture infective doses of either capuchin isolate. Neutralizing antibody to the capuchin isolates was detected in sera from 8 of 17 capuchin monkeys but not in sera from 16 humans, 15 chimpanzees, and 10 spider, 6 rhesus, and 5 squirrel monkeys.

Animals↗

Kids vs. commercials.

A game show with fifth and sixth graders effectively demonstrated their ability to critically evaluate television commercials about health-related products. While the family physician is in a unique position to affect future drug utilization patterns of children by counseling parents, a more active role, such as this exercise in the evaluation of TV messages, may be even more effective.

Advertising↗

Training predelinquent youths and their parents to negotiate conflict situations.

In response to parental requests for assistance in dealing with adolescent problem children, three parent-child pairs were taught negotiation responses to hypothetical conflict situations using behavior rehearsal and social reinforcement. The negotiation process was separated into component behaviors that were practised during simulations by each youth and his parent under the direction of trainers. Results indicated that (a) the procedures were successful in training youths and their parents in negotiation behaviors that produced agreements to conflict situations, and (b) these behaviors generalized to actual conflict situations in subjects' homes.

Adolescent↗

Financing health care in the Sudan: some recent experiments in the central region.

The macroeconomic difficulties facing the developing countries are having a direct impact on these countries' public health programs. Reduced budgets and rising demands for health care are forcing health ministries to either cut back on already inadequate health care services or identify alternative sources of revenue. This article describes and analyzes a set of experiments designed and implemented by the Sudan's Central Province that have effectively raised the operating budget of the regional health ministry. The seven experiments encompass imposition of fees, cost containment efforts, and local taxes earmarked for health. Together, the revenue generating efforts have improved the efficiency of service delivery, ensured more efficient resource allocation, raised much needed revenue for the health system, and honored the government's commitment to make free health care available to the Sudanese population.

Costs and Cost Analysis↗

Educating APNs for implementing the guidelines for adolescents in Bright futures: guidelines of health supervision of infants, children, and adolescents.

As the scope of what constitutes health and the range of determinants of health-promoting and compromising behaviors among adolescents are expanded, APNs must be well prepared to be powerful influences in the lives of all adolescents. The guidelines offered by Bright Futures challenge nurse educators to prepare APNs who possess the core competencies to knowledgeably address the health issues and concerns of all adolescents in multiple settings. The American Academy of Nursing Expert Panel's recommendations contained herein, if implemented, will further enhance the capabilities of graduate programs to prepare APNs to provide developmentally and culturally relevant disease prevention and health promotion care to adolescents and their families.

Adolescent↗