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Biomedical subjects

M A Lavelle

Publications and source records attributed to M A Lavelle.

13 recordsLinked to original sources
PubMed2004

In vitro biopsy of colorectal carcinomas.

OBJECTIVE: To determine the best part of an ulcerated colorectal neoplasm from which to take a biopsy in order to prove that the lesion is invasive. PATIENTS AND METHODS: In this experimental study, biopsies were obtained from 50 ulcerated colorectal tumours using colonoscopic biopsy forceps on the resected specimen after major colorectal resections. Four biopsy sites were chosen, the junction between the normal mucosa and the rolled edge, the top of the rolled edge, the junction between the rolled edge and the ulcer base, and the centre of the ulcer. A code was used so that the pathologist was not aware of the site of each biopsy. RESULTS: Biopsies from the very edge of the lesion were positive for carcinoma in 16% of cases, from the top of the roll in 64%, from the inner aspect of the roll in 88% and from the centre of the ulcer in 90%. CONCLUSION: Biopsies from ulcerated colorectal carcinomas are more likely to be positive if taken from the centre of the lesion, rather than the very edge.

Adenocarcinoma↗
PubMed1996

Surgical treatment of cystic swellings of the scrotum under local anaesthesia.

Fifty-one patients underwent surgery for symptomatic epididymal cysts or hydroceles, using local anaesthesia with no sedation and no diathermy. Of the patients surveyed, 91% found the procedure comfortable or uncomfortable, 9% finding it painful. Most patients (89%) were fully recovered after 3 weeks. None of the patients had to have operative intervention for complications. Treatment of these conditions under local anaesthesia is cost-effective, and can be performed with the minimum of special equipment on patients who might otherwise be unfit for a general anaesthetic.

Adult↗
PubMed1986

The significance of supraclavicular fossa node recurrence after radical mastectomy.

The clinical and pathologic features of 35 patients who had ipsilateral supraclavicular node (SCF) recurrence after radical mastectomy were reviewed. These were compared with the features of 70 patients who had a local skin recurrence after radical mastectomy, 48 of whom had a single nodule and 22 of whom had multiple skin nodules. There were no significant differences between age at diagnosis, disease-free interval, menstrual status, tumor type and grade, and extent and location of axillary node metastases in the three groups. Survival of the SCF group was intermediate between those of the single-nodule and multiple-nodule groups. SCF recurrence is an almost invariable signal of micrometastatic disease; thus, such patients are ideal candidates for trials of adjuvant therapy.

Actuarial Analysis↗
PubMed1984

Hypercalcaemia. Parathyroidectomy.

We have found the following points to have been to help in the surgery of these elusive glands: Working with a physician who has an interest in calcium metabolism Using methylene blue preoperatively Making the collar incision slightly lower than that for a thyroid operation Using a stitch in the lateral border of the thyroid gland to pull it forwards and medially Looking for the parathyroid glands in fat Assuming that the first operation is going to be the only operation.

Diagnosis, Differential↗