Letter: Therapeutic use of peritoneal cells.
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Adult↗
Biomedical subjects
M A Khalil
Publications and source records attributed to M A Khalil.
Intrathoracic presentation of amebic liver abscess.
Amebic infection is endemic in tropical and subtropical countries and still remains a common cause of chronic morbidity in these areas. This is a report of 10 patients with different intrathoracic presentations of amebic liver abscess who were treated surgically after conservative measures had failed. Five of these patients had empyema when first seen, 3 had lung abscess, and 1 had intrathoracic shadow that proved on exploration to be an amebic liver abscess. All of these 9 patients had abscesses on the right side secondary to amebic liver abscess of the right lobe of the liver. The tenth patient had amebic pericarditis secondary to amebic abscess of the left lobe of the liver. Failure of conservative treatment in these patients is attributed to the thick nature of the amebic pus and the severe reaction of the pleura and pericardium to the amebic infection. To avoid the serious complication of pleuropulmonary amebiasis, early operation is advised for large liver abscesses that are unlikely to be controlled by conservative treatment. Transpleural drainage of such abscesses gives direct approach to their sites, which are commonly located in the superior part of the right lobe of the liver. Such drainage has proved to be safe provided that the patient is receiving antiamebic drug treatment.
Adolescent↗
Lead, erythrocyte protoporphyrin, and hematological parameters in normal maternal and umbilical cord blood from subjects of the Riyadh region, Saudi Arabia.
A survey was undertaken among 124 pregnant women living in Riyadh City to investigate the passage of lead from the pregnant mother to the unborn child. The mean maternal blood lead level was 5.49 +/- 2.6 micrograms/dl and for the umbilical cord was 4.14 +/- 1.81 micrograms/dl. Lead levels were higher in maternal than in the umbilical cord blood. The results are in agreement with other studies. In this study, an excellent correlation between the maternal and cord blood lead levels (r = .83, p < .0001) confirms the transfer of lead from the mother to the fetus. A weak but significant relationship was found between maternal blood lead concentrations and birth weight of newborns (r = -.271, p < .05), and it is concluded that low levels of lead exposure to pregnant women may be considered hazardous.
Adolescent↗
African histoplasmosis: report of four cases from north-eastern Nigeria.
Four cases of African histoplasmosis with lesions of the skin, subcutaneous tissues and lymph nodes diagnosed histologically are described from the Borno State of Nigeria. Three of the cases were autochthonous to this State, whereas the fourth one originated from the Anambra State of Nigeria. These cases constitute the first record of African histoplasmosis from the arid zone of the north-eastern part of Nigeria.
Adolescent↗
Talar compression syndrome.
Ballet dancers frequently stand on the tips of their toes in the en pointe and demi pointe positions, resulting in compression of the posterior structures of the ankle during repeated plantar flexion of the foot, producing the talar compression syndrome. This mechanism may result in posterior block or impingement of an os trigonum or Stieda's process. When the dancer attempts to force the foot into plantar flexion, the os trigonum or the Stieda's process may be impinged between the calcaneus and the posterior edge of the tibia. Pain and tenderness are localized at the posterolateral aspect of the ankle behind the peroneal tendons. In nondancing members of the population, these conditions are usually asymptomatic. It is the requirement of the classical dance for a well-pointed foot that produces symptoms. We are reporting up to 7 years' followup of six professional ballet dancers in whom we removed the os trigonum for symptomatic talar compression syndrome, caused by the trauma of the en pointe position of toe dancing. Two patients had bilateral operations. All six patients returned to professional dancing within a few months and remained asymptomatic. The anatomy of this condition is reviewed, as well as the diagnosis and treatment.
Adult↗
Thioglycolic acid and pyrazole derivatives of 4(3H)-quinazolinone: synthesis and antimicrobial evaluation.
New derivatives of 4(3H)-quinazolinone were synthesized and evaluated for their antibacterial and antifungal activity. The derivatives are: 3-Aryl-2-[3-aryl-1-(carboxymethylthio)-3-oxopropyl)]-4(3H)-quinazolinones 2a-f; 3-Aryl-2-(3-aryl-1H-pyrazol-5-yl)-4(3H)-quinazolinones 3a-f; 3-Aryl-2-(1,3-diaryl-1H-pyrazol-5-yl)-4(3H)-quinazolinones 4a-f; 3-Aryl-2-(3-aryl-1-thiocarbamoyl-1H-pyrazol-5-yl)-4(3H)-quinazolinones 5a-f; 3-Aryl-2-[3-aryl-1-(carboxymethylthio)-3-hydroxyiminopropyl)]-4(3H)- quinazolinones 6a-f; and 3-Aryl-2-[3-aryl-1-(carboxymethy- lthio)-3-thiocarbamoyliminopropyl)]-4(3H)-quinazolinones 7a-f. Some of the tested compounds showed activity comparable to that of the standard references used.
Anti-Bacterial Agents↗
Synthesis of some 1,2,4-triazolo [3,4-b] [1,3,4]thiadiazoles as potential anthelmintics.
Two novel series of triazolothiadiazole derivatives were synthesized, namely: 6-substituted-3-(4-substituted phenoxymethyl)-1,2,4-triazolo[3,4- b] [1,3,4]thiadiazoles and 6-mercapto-3-(4-substituted phenoxy-methyl)-1,2,4-triazolo[3,4- b] [1,3,4]thiadiazoles. The anthelmintic activity of representative compounds was studied.
Animals↗