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Biomedical subjects

M A Haque

Publications and source records attributed to M A Haque.

42 records · Page 3Linked to original sources

Preponderance of beta adrenergic receptors in the gastric fundus of the rat.

There are two kinds of adrenergic receptors in rat fundus (stomach), the alpha receptors are stimulated with adrenaline and noradrenaline and can be blocked effectively with azapetine and the beta receptors are stimulated with isoprenaline and adrenaline and can be blocked effectively with propranolol. Adrenaline, noradrenaline and isoprenaline all produce inhibition of acetylcholine induced contractions in both untreated and reserpinized tissues that can be antagonized with azapetine and propranolol on its specific receptors but propranolol has a greater capacity to decrease the sensitivity of both untreated and reserpinized tissues to isoprenaline and adrenaline than azapetine can in case of noradrenaline and adrenaline.

Acetylcholine↗

Effects of reserpine on the responses of the isolated rat fundus strip to catecholamines and specific adrenoceptor antagonists.

The effects of reserpine on the sensitivity to catecholamines and adrenoceptor antagonists propranolol and azapetine were studied on the fundus strips of the rat. The results obtained in this study would support the view that reserpine may increase the sensitivity of beta receptor to isoprenaline and adrenaline by the mechanism which may be independent of the uptake of catecholamines in the sympathetic nervous system.

Animals↗

Comparisons between invasive and noninvasive determinations of embryonic heart rate in chickens.

The embryonic heart rate (HR) of chicken eggs was determined by ballistocardiography, electrocardiography, impedance-cardiography and acoustocardiography. The effects of these different methods on the HR were examined for young (12-day-old) and late (16- and 18-day-old) embryos. Ballistocardiography is a non-invasive method. Nevertheless, the mean HRs determined using this method at 5-hr intervals were significantly different in many embryos. This difference was caused by the natural variability of embryonic HR. The statistical analyses indicated that any of these four methods did not influence the HR measurement and can be used as a simple means for determination of the embryonic HR.

Acoustic Stimulation↗

Field studies on the sensitivity and specificity of an immunochromatographic test for the detection of Plasmodium falciparum malaria in tribal areas of Orissa.

A rapid immunodiagnostic test developed by an Australian Biotechnology company for the diagnosis of Plasmodium falciparum in the peripheral blood has been evaluated in the field for its sensitivity, specificity and efficacy in comparison to microscopic examination. The results showed that the tests sensitivity, specificity and efficacy were 98.2, 96.9 and 97.5 per cent respectively. The positive and negative predictive values of the test were 96.4 and 98.4 per cent respectively. The test when compared to the conventional microscopy did not show any statistically significant difference suggesting that the two diagnostic methods are equally good. The test performed did not show cross-reactions with other parasite species. It is a simple and rapid field diagnostic method, which does not require any expensive laboratory equipment or skilled personnel.

Antigens, Protozoan↗