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Biomedical subjects

M A Frable

Publications and source records attributed to M A Frable.

36 records · Page 2Linked to original sources

Epidermoid cyst of the frontal bone masquerading as frontal sinusitis.

Epidermoid cysts occur whenever two epidermal surfaces fuse together during early intrauterine life and an ectodermal implant is retained deep to the surface. They are very slow growing and symptoms may not occur till middle age. The authors present a patient whose symptoms of frontal headache were mistaken for frontal sinusitis for over 10 years. The patient's symptoms were completely relieved by surgical excision of an epidermoid cyst of the frontal bone.

Adult↗

Fine-needle aspiration biopsy: efficacy in the diagnosis of head and neck sarcoidosis.

The authors report the usefulness of fine-needle aspiration biopsy to establish the diagnosis of sarcoidosis in patients with palpable disease in the head and neck areas. Aspiration biopsy proved to be a simple and quick method for establishing this diagnosis in the eight cases reported in this series. Interpretation of cytologic smears with identification of typical sarcoid-like granulomas proved to be quite easy. No complications occurred secondary to use of this technique.

Adult↗

Conjoint hyoid bone segments for the repair of severe laryngeal stenosis.

We discuss and show by illustrations a surgical technique for the management of severe combined laryngeal and subglottic stenosis using multiple pieces of hyoid bone. No serious problems resulted from the removal of the entire hyoid bone. All patients have maintained a good airway, despite the possibility of absorption of a free bone graft. Although it is reasonable to try to use the hyoid bone with a strap muscle pedicle, it is impossible to reconstruct the subglottic and laryngeal area without multiple pieces. Our experience encourages us to use multiple pieces of free hyoid bone for laryngotracheal reconstruction.

Adult↗

Severe laryngeal stenosis repair: long-term follow-up using conjoint hyoid bone segments.

In early 1983 the authors presented an innovative procedure for the management of severe laryngeal stenosis. Because of the severity of the stenosis and the large surgical defect created by excision of the stenosis, multiple pieces of the hyoid bone were sewn together conjointly to bridge the surgical defect. The authors are now able to report follow-up in 6 patients ranging from 11 to 60 months and discuss their favorable experience with this procedure.

Adult↗

Fine-needle aspiration biopsy revisited.

Between November 1972 and December 1981, 1303 fine needle aspiration biopsies were performed on patients with head and neck masses at the Medical College of Virginia, Virginia Commonwealth University. The results of 649 lymph node, 227 salivary gland, 286 thyroid, and 41 miscellaneous aspiration biopsies are reviewed. No radical treatment resulted from false positive diagnoses and no patient delay in treatment occurred because of false negative results. Techniques for performing the procedure are briefly reviewed. Cost containment is stressed, particularly the savings that occur when the diagnosis is not neoplastic. Future developments and uses of the procedure are discussed.

Biopsy, Needle↗

Thin needle aspiration biopsy of the thyroid gland.

Between 1973 and December 1978, the authors performed 133 thin needle aspiration biopsies of the thyroid gland. Thin needle aspiration biopsy has proved valuable in this series and may save some patients the necessity of thyroid surgery. The procedure, performed quickly, results in a diagnosis usually available minutes later, and a definite patient disposition can be made promptly. At a time of medical cost containment, this procedure will become more important in patient care. Review of our aspirations through 1977 revealed three false negative biopsies and two false positive reports. Important differential characteristics between follicular neoplasm and nodular or adenomatous goiter will be discussed. Neoplasms appear to represent a smaller percentage of cold thyroid nodules than reported elsewhere.

Biopsy, Needle↗

Thin-needle aspiration biopsy: the diagnosis of head and neck tumors revisited.

Results of 567 thin-needle aspiration biopsies of head and neck lesions are reviewed. Cases included lymph nodes, salivary glands, thyroid, soft tissue and bone lesions. For the entire series, 17 patients had unsatisfactory aspirations. There were 12 false negative reports and 4 false positive reports, rates of 2.1% and 0.7%, respectively. No radical treatment resulted from false positive diagnoses and no patient delay in treatment occurred because of false negative reports. In the case of benign and malignant tumors, reports were histologically specific in more than 98% of the cases. This technique is simple to perform and saves time and hospital costs. Thin-needle aspiration biopsy can be effectively used in the management and diagnosis of head and neck tumor patients where close cooperation of the clinician and cytopathologist exists.

Biopsy, Needle↗

Neurilemmoma of the auricle: a case report.

A report of a case of a solitary benign neurilemmoma of the auricle is presented. It is believed to be the first such documented case. Its nature, histology, and differential diagnosis is reviewed. It is suggested that "neurogenic tumors" be added on to the current classification of auricular masses.

Adolescent↗

Granular cell myoblastomas.

Granular cell myoblastoma is an uncommon benign tumor. The diagnosis is rarely suspected preoperatively, and the clinician is frequently baffled or frightened by an unfamiliar diagnosis. Twenty-eight patients with the diagnosis of granular cell myoblastoma presented for treatment at Richmond Eye and Ear Hospital and the Medical College of Virginia Hospitals between January 1, 1952, and December 31, 1974. The authors believe that this is one of the largest series of cases reported in the world literature. The tumor presents most often in the fourth decade of life and about equally in the sexes. Of interest is the nearly 5:1 predominance in the Negro race compared to the Caucasian race.

Adolescent↗

Virus infections of the respiratory tract cytopathologic and clinical analysis.

Thirty-three cases of respiratory tract virus infections diagnosed cytologically are reviewed. The clinical and demographic data are presented and correlated with an analysis of the cytologic findings. Herpes virus was the most common infection. It occurred in patients with other severe medical problems and had little apparent effect on the clinical outcome of any particular case. Quantitative and qualitative cytologic findings did not correlate with the severity of the herpetic infection. The virus was isolated in culture in only one of 21 cases of Herpes virus infection. Cases in the later part of the study indicate an increasing incidence or recognition of the infection in the respiratory tract. In this series there was a clustering of Herpes virus cases in relation to date of admission and hospitalization in respiratory intensive care. Cytomegalovirus infection was recognized in four cases. This infection occurs in the immune suppressed patient and can be made reliably from cytologic findings. Smears must be screened thoroughly and carefully as the characteristic inclusion is seen in only a rare cell. Bronchial brushing specimens are the most useful. The disease should not be fatal if the level of immune suppression can be manipulated and the patients basic medical problem is not too severe. Cytologic findings contribute little information to tjor medical problems and the adenovirus infection was incidental. Thy cytologic findings in some cases may be non-specific since antibody studies and culteral confirmation are lacking in these cases.

Adenoviridae Infections↗

Fine needle aspiration biopsy in the diagnosis of sarcoid of the head and neck.

The use of fine needle aspiration biopsy to confirm the clinical diagnosis of six cases of sarcoidosis with palpable disease in the head and neck area is reported. The procedure was simple and inexpensive, and the interpretation of the smears and identification of typical sarcoid granulomas was easy.

Biopsy, Needle↗