Diagnostic value of blind percutaneous liver biopsy in obstructive jaundice.
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Biomedical subjects
Publications and source records attributed to M A Atoba.
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Chronic peptic duodenitis accounted for four percent of endoscopic diagnoses of upper gastrointestinal disorders in lbadan, Nigeria. This clinicopathologic entity was a frequent cause of x-ray negative dyspepsia and was a cause of significant bleeding in two of the 26 patients included in this study. None progressed to frank duodenal ulceration during the follow-up period. It is emphasized that accurate assessment of dyspepsia must include endoscopic and histologic examinations.
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The factors in the aetiology of Hepatic Encephalopathy in the tropics were analysed from the medical and necropsy records of 103 patients. Internal bleeding and infections were the commonest precipitating factors.
Forty-six patients with HBs-Ag negative acute hepatitis were divided into 2 equal groups in a prospective study. Hepatitis in 12 of the patients (6 in each group) was secondary to septicaemia, while the hepatitis in the remaining 34 patients were of viral aetiology. Patients in the first group received essential phospholipid choline capsules (EPLC Group) for a six weeks period while those in the control group received vitamin B complex capsules over the same period. Essential phospholipid choline (EPLC) was found to hasten recovery in those with viral hepatitis while the drug showed no added advantage in those with hepatitis due to septicaemia.
A total of 237 patients with confirmed malignancies of the upper-gastrointestinal tract (UGIT) were studied. Of these, 143 (60.34%) were gastric cancers, 66 (27.85) were oesophageal malignancies and 28 (11.81%) were in the small intestine. Epigastric pain accompanied by vomiting after meals was the commonest first symptom in patients of gastric cancer whereas dysphagia formed the commonest first symptom in oesophageal cancer. However, no definite first symptom could be attributed to those with small intestinal tumors. As many as 134 patients (56.54%) had advanced malignancies at presentation itself. The usefullness of first symptoms in early diagnosis and prognosis is discussed.
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