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Biomedical subjects

Lorin P Maletsky

Publications and source records attributed to Lorin P Maletsky.

5 recordsLinked to original sources

Accuracy of an optical active-marker system to track the relative motion of rigid bodies.

The measurement of relative motion between two moving bones is commonly accomplished for in vitro studies by attaching to each bone a series of either passive or active markers in a fixed orientation to create a rigid body (RB). This work determined the accuracy of motion between two RBs using an Optotrak optical motion capture system with active infrared LEDs. The stationary noise in the system was quantified by recording the apparent change in position with the RBs stationary and found to be 0.04 degrees and 0.03 mm. Incremental 10 degrees rotations and 10-mm translations were made using a more precise tool than the Optotrak. Increasing camera distance decreased the precision or increased the range of values observed for a set motion and increased the error in rotation or bias between the measured and actual rotation. The relative positions of the RBs with respect to the camera-viewing plane had a minimal effect on the kinematics and, therefore, for a given distance in the volume less than or close to the precalibrated camera distance, any motion was similarly reliable. For a typical operating set-up, a 10 degrees rotation showed a bias of 0.05 degrees and a 95% repeatability limit of 0.67 degrees. A 10-mm translation showed a bias of 0.03 mm and a 95% repeatability limit of 0.29 mm. To achieve a high level of accuracy it is important to keep the distance between the cameras and the markers near the distance the cameras are focused to during calibration.

Biomechanical Phenomena↗

The effect of valgus/varus malalignment on load distribution in total knee replacements.

Valgus or varus malpositioning of the tibial component of a total knee implant may cause increased propensity for loosening or implant wear and eventually may lead to revision surgery. The aim of this study was to determine the effect of valgus/varus malalignment on tibio-femoral mechanics during surgical trial reduction and simulated gait loading. In seven cadaver legs, posterior cruciate sparing total knee replacements were implanted and tibial inserts representing a neutral alignment and 3 degrees and 5 degrees varus and valgus alignments were sequentially inserted. Each knee with each insert was loaded in a manner representative of a trial reduction performed during knee surgery and loaded in a physiological knee simulator. Simulated gait performed on the simulator demonstrated that internal/external and adduction/abduction rotations showed statistical changes with some of the angled inserts at different points in the walking cycle. Neither medial/lateral nor anterior/posterior translations changed statistically during simulated walking. The pressure distribution and total load in the medial and lateral compartments of the tibial component changed significantly with as little as a 3 degrees variation in angulation when loaded in a manner representative of a trial reduction or with a knee simulator. These results support the need for precise surgical reconstruction of the mechanical axis of the knee and proper alignment of the tibial component. These results further demonstrate that tibial contact pressures measured during a trial reduction method may be predictive of contact mechanics at the higher loading seen in the knee simulator.

Arthroplasty, Replacement, Knee↗

Computational modelling of a total knee prosthetic loaded in a dynamic knee simulator.

Dynamic knee simulators attempt to reproduce the estimated forces, moments, and motions of both the patello-femoral and tibio-femoral joints during ambulatory activities. As a continuation of work designed to reproduce desired three-dimensional joint loading and motion on a dynamic knee simulator, the goal of this study was to develop a computational model of a prosthetic knee placed within an existing computational model of a dynamic knee simulator. The resulting model was then used to produce inputs to the controllable axes of the simulator for reproduction of desired knee loading and motion. Previously, a three-dimensional computational model of the simulator was developed and verified using a simplified and instrumented analog knee. The work presented here replaced the simplified and constrained geometries of the analog knee with structures representing a prosthetic knee. Three-dimensional geometries were determined based on digitized surface points of a right total knee replacement. Deformable contacts between the articulating surfaces of the tibio-femoral and patello-femoral joints were then defined and model sensitivities were identified. Predicted results from the computational model were compared to experimental results for force profiles applied at the simulator's controllable axes. Within identified limitations, the model was then used to generate inputs to the simulator to reproduce desired patellar tendon load during a squat and desired out-of-sagittal-plane motion during a squat.

Arthroplasty, Replacement, Knee↗

Simulating dynamic activities using a five-axis knee simulator.

This work describes the design and capabilities of the Purdue Knee Simulator: Mark II and a sagittal-plane model of the machine. This five-axis simulator was designed and constructed to simulate dynamic loading activities on either cadaveric knee specimens or total knee prostheses mounted on fixtures. The purpose of the machine was to provide a consistent, realistic loading of the knee joint, allowing the kinematics and specific loading of the structures of the knee to be determined based on condition, articular geometry, and simulated activity. The sagittal-plane model of the knee simulator was developed both to predict the loading at the knee from arbitrary inputs and to generate the necessary inputs required to duplicate specified joint loading. Measured tibio-femoral compressive force and quadriceps tension were shown to be in good agreement with the predicted loads from the model. A controlled moment about the ankle-flexion axis was also shown to change the loading on the quadriceps.

Arthroplasty, Replacement, Knee↗

Computational modeling of a dynamic knee simulator for reproduction of knee loading.

As a first step towards reproducing desired three-dimensional joint loading and motion on a dynamic knee simulator, the goal of this study was to develop and verify a three-dimensional computational model that generated control profiles for the simulator using desired knee loading and motion as model inputs. The developed model was verified by predicting tibio-femoral loading on an instrumented analog knee for given actuator forces and the ability to generate simulator control profiles was demonstrated using a three-dimensional walking profile. The model predicted axial tibia loading for a sagittal-plane dual-limb squat within 1% of measured peak loading. Adding out-of-sagittal-plane forces decreased the accuracy of load prediction. The model generated control profiles to the simulator that produced axial tibia loading within 16% of desired for walking. Discrepancies in predicted and measured quadriceps forces influenced the accuracy of the generated control profiles. Future work will replace the analog knee in both the model and machine with a prosthetic knee.

Biomimetics↗