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Leo Semes

Publications and source records attributed to Leo Semes.

4 recordsLinked to original sources
PubMed2006

The relationship among race, iris color, central corneal thickness, and intraocular pressure.

PURPOSE: Central corneal thickness (CCT) influences applanation intraocular pressure (IOP) measurement. The present study sought to determine whether iris color might represent a qualitative surrogate for CCT or race, and therefore differential risk for elevated IOP and, consequently, developing glaucoma. METHODS: Eligible patients included those with best-corrected visual acuity (BCVA) better than 20/40 and who had not worn contact lenses within 24 hours. Exclusion criteria were prior ophthalmic surgery, topical ocular or systemic medication that would influence IOP, previous ocular inflammatory conditions, or current treatment for ophthalmic treatment. Data collection included demographic (name, date of birth, race), BCVA, and iris color. Iris color was judged according to a purpose-developed chart (white: blue, green, brown or black: brown) and patients were assigned to one of four groups. Goldmann applanation tonometry and pachymetry measurements were performed consecutively. To attain a power of 90% to find a difference of 40 microm with alpha < 0.05, we examined at least 14 subjects (28 eyes) for each group. RESULTS: Comparing pachymetry measurements among iris colors revealed no statistically significant difference among the three groups of whites: blue (552 microm), green (552 microm), and brown (562 microm). The same held true when comparing IOP and CCT-adjusted IOP with iris color: blue-15.2, 15.1, green-15.4, 15.2, and brown-14.7, 14.0. When comparing CCT between whites and blacks, CCT was significantly thinner in blacks (533 microm), whether evaluating all whites (555 microm, p = 0.03) or comparing only the brown-iris white group with the black group (562 microm vs. 533 microm, p = 0.03). Mean CCT-adjusted IOP was barely significantly different between whites (14.8) and blacks (16.7) (p = 0.04). CONCLUSION: These results suggest that iris color is not associated with CCT and apparently iris color does not influence measured IOP. We were able to establish a relationship between race and IOP when adjusting IOP for CCT. Our data show a significantly higher CCT-adjusted IOP for blacks than whites demonstrating a racial difference in CCT-corrected IOP.

Adolescent↗
PubMed2003

The reliability of frequency-doubling technology (FDT) perimetry in a pediatric population.

PURPOSE: Frequency-doubling Technology IFDT) Perimetry was introduced as a rapid, easy method for detection of visual-field defects in adults. Its reliability, howev, has never been tested among pediatric patients. The purpose of this study was to determine if children could complete a screening program of FDT Perimetry reliably and to define the age range over which it might be most applicable. METHODS: Two hundred fifty-nine normal children (mean age, 10.7 years; range, 4 to 17 years) were asked to complete the FDT C-20-1 screening test as part of their general eye examination. The visual-field results were analyzed for reliability using the number of false-positive errors, fixation losses, and visual-field defects. For the purposes of this analysis, field results were considered unreliable with false-positives > or = 1 or fixation errors > or = 1. The visual-field test was also considered unreliable if > 2 sectors were flagged. RESULTS: Data from 254 children were included in the analysis. Five children were excluded because of suspected malingering or ocular health diagnosis that may have produced a visual-field defect. False-positives were less than one for all but the youngest age group 14 years old). Fixation errors decreed with increasing age and fell below one (became reliable) at approximately 9 years of age, and remained less than one through 17 year. Visual-field loss for purposes of this study when present in more than two sectors was considered unreliable in this normal population. CONCLUSIONS: Children ages 10 years of age and older can reliably complete the FDT C-20-1 screening field test using the strictest criteria, combining false-positives, fixation losses, and visual-field losses. These data are derived from normal subjects, who on complete eye examination, had no ocular disease or reason to suspect visual-field defects.

Adolescent↗
PubMed2002

The relationship among axial length, corneal curvature, and ocular fundus changes at the posterior pole and in the peripheral retina.

BACKGROUND: The purpose of this study was to investigate whether fundus findings in moderately to highly myopic eyes are more likely to occur in the posterior pole or peripheral retina and to describe the type and frequency of ocular fundus variations. METHODS: Patients qualified for inclusion if the refractive error was 6.00 D or greater of myopia or the axial length was 26 mm or greater Data collection included refractive correction, corneal curvature, axial length, and stereoscopic ocular fundus evaluation. RESULTS: Twenty eyes of 10 male patients and 36 eyes of 20 female patients met eligibility criteria. Mean age of all subjects was 36 +/- 15 years (range, 17 to 83 years). All eyes had best-corrected visual acuity of at least 20/25. Spherical equivalent refractive correction (SERC) was -8.07 +/- 2.11 diopters (range, -6.37 to -16.00) and -7.92 +/- 2.27 diopters (-5.50 to -16.00) for right and left eyes, respectively. Mean axial length was 26.39 +/- 1.14 mm (range, 24.27 to 30.02) and 26.36 +/- 1.26 mm (range, 24.41 to 30.67) for right and left eyes, respectively. Of 56 eyes examined, 25 (44.7%) exhibited only findings at the posterior pole alone; 13 eyes (23.2%) had no findings by our criteria; 12 eyes (21.4%) had findings in the periphery alone; and 6 eyes (10.7%) had posterior-pole and periphery findings. CONCLUSIONS: This study demonstrates that fundus findings in moderately to highly myopic eyes were more prevalent in the posterior pole alone versus the retinal periphery alone, or than those occurring in both the posterior pole and retinal periphery. This study also confirms that the most-prevalent posterior pole lesion is optic nerve head (ONH) crescent and the most-frequent peripheral retinal change is lattice degeneration. This information may be useful when evaluating and following patients with moderate-to-high degrees of myopia-especially after surgical refractive modification.

Adolescent↗