Biomedical subjects
Lein-Ray Mo
Publications and source records attributed to Lein-Ray Mo.
Synchronous esophageal squamous carcinomas.
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Endoscopic resection of an ectopic Warthin's tumor in the esophagus.
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Villous adenoma of entire biliary tree.
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Choledochocele and common bile duct stones.
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Villous adenoma of common bile duct.
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Endoscopic management of bleeding from colonic Dieulafoy-like lesion.
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Preoperative endoscopic sphincterotomy in the treatment of patients with cholecystocholedocholithiasis.
Preoperative endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy (ES) prior to laparoscopic cholecystectomy (LC) are the most common methods for the diagnosis and treatment of patients with cholecystocholedocholithiasis. We evaluated the selection criteria for preoperative ERCP examination and the results of endoscopic-laparoscopic treatment of patients with choledocholithiasis. Between January 1993 and December 1998, 1630 patients with symptomatic cholelithiasis were admitted for surgical intervention. Preoperative ERCP was performed in 247 patients according to the selection criteria. The criteria to perform ERCP were dilated common bile duct (CBD; more than 8 mm), abnormal serum liver test results, and a recent history of pancreatitis. Endoscopic sphincterotomy (ES) was performed if CBD stones were found during the procedure. LC was then carried out within 3 days after ES. Of the 247 patients selected for preoperative ERCP, CBD stones were confirmed in 146 patients (59.1%). ES was successful in 141 patients, and stone clearance was achieved in 133 patients, resulting in a 94.3% success rate. Eight patients (5.5%) had complications after endoscopic intervention, all of which resolved uneventfully. Open operative procedures were carried out in a total of 31 patients. Overall, 115 patients were successfully treated by this endoscopic laparoscopic sequence. The length of hospital stay in these groups was significantly lower than that for patients in whom an open method was employed. Preoperative ES combined with LC is a safe and effective therapy for cholecystocholedocholithiasis, and the criteria that we used for the selection of patients seem to be appropriate.
Acute pancreatitis caused by hemobilia secondary to hepatoma with bile duct invasion.
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Signet ring cell carcinoma of major papilla.
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Balloon sheath miniprobe compared to conventional EUS in the staging of colorectal cancer.
BACKGROUND/AIMS: Conventional endoscopic ultrasonography was a valuable modality in staging the invasion depth of colon cancer. However, it is not widely used because of its difficulty in detecting small or flat lesions and obtaining a cross-sectional image due to tight stricture of tumor lesions and in those lesions located at or over a bend of the colon. Due to this, mistaging or understaging is often seen. We conducted a prospective study using a new technique and instrument (balloon sheath with miniprobe) in colon cancer staging and compared it with the conventionally used endosonography. METHODOLOGY: One hundred and thirty-four patients underwent preoperative staging using two different instruments. Seventy-three patients were evaluated with conventional endoscopic ultrasonography while the other 61 patients were evaluated with the balloon sheath miniprobe. RESULTS: The balloon sheath miniprobe had an overall accuracy rate of 85%; 100% in T1; 78% in T2; 90% in T3 and 40% in T4. Lymph node metastasis was correctly determined in 67% with a sensitivity and specificity rate of 56% and 75%, respectively. The overall accuracy rate of endoscopic ultrasonography in staging colon carcinoma was 89%; 83% in T1; 83% in T2; 93% in T3 and 71% in T4. Overall accuracy rate in lymph node metastasis evaluation was 77%. Sensitivity was 77% and specificity was 76%. Inability to obtain a clear cross-sectional image using the miniprobe was 3.3%, while that of the endoscopic ultrasonography was 11%. CONCLUSIONS: The balloon sheath miniprobe is a good alternative for evaluating lesions over the proximal colon and is superior to other modalities in obtaining a cross-sectional image even in tight, stenotic lesions. One limitation is its difficulty in assessing deeper structures such as lymph node groups and contiguous organ involvement.