Biomedical subjects

L Wofsy

Publications and source records attributed to L Wofsy.

30 records · Page 2Linked to original sources

PubMed1973

Affinity labeling of anti-Group A streptococcal polysaccharide antibodies.

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Animals↗

PubMed1972

Cell separation on affinity columns: the isolation of immunospecific precursor cells from unimmunized mice (lactoside hapten-lymphocyte receptors-immunology).

We have used affinity columns to isolate from the spleens of unimmunized mice a population of lymphocytes that specifically bind a lactoside hapten. These cells are able to initiate an antibody response to azophenyl-beta-lactoside when transferred to appropriate irradiated recipients.

Animals↗

PubMed1971

Chemical approaches to the cell receptor problem.

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Acrylamides↗

PubMed1971

Cell separation on affinity columns: the preparation of pure populations of anti-hapten specific lymphocytes.

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Acrylates↗

PubMed1970

Specific separation of cells on affinity columns.

Cell filtration is performed on affinity columns prepared by the chemical modification of large polyacrylamide beads. Affinity columns selectively bind cells that produce antihapten antibodies of corresponding specificity, while cells without the specific antihapten sites pass through freely and are recovered quantitatively in the eluate. The binding of the antihapten specific cells is inhibited by hapten. Such cell filtration affinity columns may be useful in specifically purifying cell populations with characteristic membrane-receptor proteins.

Acrylic Resins↗

PubMed1970