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Biomedical subjects

L Wernstedt

Publications and source records attributed to L Wernstedt.

3 recordsLinked to original sources
PubMed1979

Cefaclor therapy in acute exacerbations of chronic bronchitis.

Twenty-four patients with acute exacerbations of chronic bronchitis were treated with cefaclor at a dose of 500 mg every 8 hours for 10 days. Studies included volume, appearance and bacteriological examination of sputum, and haematological and virus serology tests. The response to therapy was judged on the reduction in sputum volume or the conversion of its character from purulent to mucoid. Nineteen of 24 patients improved and in 4 of 5 failures, positive serology for influenza virus was found. Growth of Pseudomonas occurred in one sputum. Minor side effects were seen in 3 patients, and no haematological or biochemical abnormalities were found.

Acute Disease↗
PubMed1978

Radiographic appearance of mycoplasmal pneumonai.

As there are contradictory opinions on the radiographic appearance of mycoplasma pneumonai, the chest examination of 59 patients with at least a fourfold increase of the complement fixation titer were studied retrospectively. The investigation shows that there is a great variety of radiologic patterns from interstitial, disseminated infiltrates to total lobar consolidation. The alveolar pattern seems to be more common in women, but there is no relation to age, duration, season or bacterial superinfection. A development from interstitial infiltrates to alveolar changes or vice versa during the course of the illness was not confirmed in this study. The radiographic variability may be explained by the alveolar infiltrates being an inflammatory reaction to Mycoplasma pneumoniae, and the interstitial densities being an immunologic response. No definite difference between bacterial and mycoplasmal pneumonias was observed, but a multitude of alveolar infiltrates speaks for a mycoplasmal origin.

Adolescent↗