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Biomedical subjects

L Weinstein

Publications and source records attributed to L Weinstein.

At least 271 records · Page 15Linked to original sources
PubMed1967

Purified staphylococcal alpha toxin: effect on epithelial ion transport.

Purified staphylococcal alpha toxin, when added to the serosal bathing medium of the isolated toad bladder, causes a rapid fall in short-circuit current and transepithelial potential difference. It has no effect when added to the mucosal bathing medium. Oxygen consumption by suspensions of minced bladder tissue is stimulated by the toxin. These effects are neutralized by staphylococcal antitoxin.

Animals↗
PubMed1967

Studies of intestinal microflora. VI. Effect of x irradiation on the fecal microflora of the rat.

The effect of sublethal, midlethal, and lethal doses of total-body X irradiation on the fecal microbial population of the rat was studied. No changes were observed in animals receiving sublethal doses of X ray. Midlethal and lethal doses produced an increase in the numbers of fecal coliforms, staphylococci, streptococci, and fungi; these changes were transient in rats that survived, but were more marked and persisted during life in those that died. The possible role of these alterations in intestinal microflora in post-irradiation infection and in death is discussed.

Animals↗
PubMed1967

Studies of intestinal microflora. VII. Effect of diet and fecal microbial flora on survival of animals exposed to x irradiation.

Changes in the numbers and ratios of bacteria in the feces of rats were produced by administration of three different diets-grain, meat alone, and meat plus lactose. After significant alterations in the intestinal flora had developed, the animals were exposed to a midlethal dose of X irradiation (1,550 R). This treatment led to 100% deaths in rats in which the numbers of coliforms were increased by diet prior to irradiation. Changes in the numbers of lactobacilli appeared to play no role in determining the responses to X-ray exposure. When little or no change was produced by diet and when "normal" microflora was present, the fatality rate was reduced to 60%, and the rate of deaths was retarded when compared with that of the animals in which coliforms were increased.

Animals↗