Search PubMed⌕ Search

Biomedical subjects

L Weinstein

Publications and source records attributed to L Weinstein.

At least 217 records · Page 12Linked to original sources

In vitro susceptibility of atypical mycobacteria to rifampin.

Atypical mycobacteria (209 strains) were examined for susceptibility to rifampin by the proportion method by using Middlebrook 7H-10 agar. All strains of Mycobacterium kansasii and tap-water scotochromogens were inhibited by 0.25 to 1 mug of the drug per ml. Seventy-six per cent of M. scrofulaceum and 61% of M. intracellulare strains were susceptible to 4 mug/ml or less; 5% of the former and 8% of the latter were resistant to 16 mug/ml. All strains of M. gastri and M. triviale and most strains of M. terrae were sensitive to 1 to 4 mug/ml. Two strains of M. borstelense were both inhibited by 8 mug/ml. Nearly all strains of M. fortuitum were resistant to the drug. The results of this study suggest that rifampin may be a valuable agent for the treatment of many atypical mycobacterial infections.

Drug Resistance, Microbial↗