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Biomedical subjects

L Weinrauch

Publications and source records attributed to L Weinrauch.

At least 37 records · Page 2Linked to original sources
PubMed1986

Topical treatment of cutaneous leishmaniasis.

Sixty-seven patients, 19 females and 48 males, 4-66 years old, suffering from lesions of cutaneous leishmaniasis were treated topically with an ointment comprising 15% paromomycin sulfate and 12% methylbenzethonium chloride in white soft paraffin (P-ointment, U.K. patent GB117237A). After 10 days of treatment, twice daily, the lesions in 72% of the treated patients were free of parasites, 15% became free within an additional 20 days, without further treatment, and 13% failed to respond. Pigmentation developed in 18% of the treated lesions and inflammation of varying degree was associated with the treatment. These developments did not affect the clinical healing process which was generally completed in a period of 10-30 days after termination of treatment. In addition, 94% of the treated lesions healed with little or no scarring. No adverse clinical or laboratory side effects were observed except for a burning sensation at the site of treatment. Parasites isolated from patients who failed to respond to topical treatment were found to be susceptible to PR-MBCl in both in vitro infected macrophages and in vivo in experimentally infected BALB/c mice.

Administration, Topical↗
PubMed1986

Psoriasis vulgaris of labium majus.

A case of psoriasis vulgaris of the labium majus in a 22-year-old woman is described. The unusual presentation and other conditions that should be included in the differential diagnosis of this common disease are emphasized.

Adult↗
PubMed1985

Primary osteoma cutis.

Primary osteoma cutis in a 24-year-old white woman presented as a small hard tumor beneath the skin of the left breast. Histologic examination of the lesion showed typical osteoma cutis. This was likely to be a case of primary osteoma cutis since the history and results of physical examination and laboratory tests failed to reveal other abnormalities.

Adult↗
PubMed1983

Cutaneous leishmaniasis: treatment with ketoconazole.

A 17-year-old boy with an eight-month history of cutaneous leishmaniasis on the left earlobe was treated with ketoconazole for a period of four weeks. The patient showed excellent improvement both clinically and protozoologically. Ketoconazole, a new imidazole bound covalently to piperazine, has been developed as a broad spectrum antimycotic agent and appears to be a good antileishmanial drug.

Adolescent↗
PubMed1982

Rifampicin treatment of cutaneous leishmaniasis.

In a small-scale preliminary trial of oral rifampicin treatment was considered successful in six out of eight cutaneous leishmaniasis patients and probably effective in a seventh. The in vitro effect of rifampicin on leishmania organisms concerns inhibition of mitochondrial function or replication. The need for protozoological control in the assessment of treatment is stressed.

Adolescent↗