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Biomedical subjects

L W Grossman

Publications and source records attributed to L W Grossman.

21 records · Page 2Linked to original sources

Internal contamination of laboratory personnel by 131I1.

Internal contamination by 131I among the personnel in a nuclear medicine laboratory was surveyed from January to July, 1979. Because of the formulation change made by the manufacturer in April to reduce volatility, it was possible to study two different therapeutic solutions of 131I. Internal contamination of personnel who administered 131I was found to be 90 times less after the reformulation. Compliance with a recent NRC regulatory guide of less than 40 nCi (1.48 kB1) of 131I thyroid burden as a quarterly average should not be difficult using the new, less volatile 131I; however, strict precautionary measures are essential to minimize contamination, which is common in the nuclear medicine environment.

Body Burden↗

Measurements of the distribution of technetium-99m sulfur colloid and technetium-99m HEDP in normal humans.

Technetium-99m sulfur colloid and technetium-99m hydroxyethylidene diphosphonate (HEDP) are two radiopharmaceuticals that have been widely used in nuclear medicine. Radiation dose estimates for both materials have been published in the literature and are found in the package inserts of the commercial kits. However, these estimates were made without the benefit of quantitative human organ uptake data. Estimates of absorbed radiation dose to the kidneys differ by nearly a factor of 6 between the two calculations for HEDP. The results of this study are in agreement with the lower previous estimate. Other than that one exception, agreement of the previous estimates with the measurements reported here is surprisingly good.

Adult↗