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Biomedical subjects

L Vizioli

Publications and source records attributed to L Vizioli.

At least 37 records · Page 2Linked to original sources

MR signal enhancement in cervical spondylotic myelopathy. Correlation with surgical results in 35 cases.

In a review of Magnetic Resonance (MR) imaging findings of 35 cervical spondylotic myelopathy patients, a localized increased signal intensity was observed within the most compressed segment of the cervical cord on T2 and proton density weighted images. Size and duration of cervical cord constriction seemed to be the predisposing factors in producing such an abnormality. All patients underwent surgery. Postoperatively the high MR signal intensity disappeared in 3 (8.6%) cases, decreased in other 20 (57.1%) cases, and did not change in the remaining 12 (34.3%) cases. Thus reversible (edema, transient ischemia) and/or irreversible (malacia, gliosis) histological changes seemed to be represented in MR signal enhancement.

Adult↗

Cord diameters and their significance in prognostication and decisions about management of cervical spondylotic myelopathy.

The cases of 35 cervical spondylotic myelopathy patients exhibiting areas of high signal intensity within the cervical cord on T2 and proton density weighted MR images were reviewed. In each case, the ratio of the anteroposterior diameter to the transverse diameter (anteroposterior compression ratio or APCR) at the most compressed segment of the cervical cord was measured on axial MR images and compared with the patient's neurological status. The patients with APCR of 40% or more had a better neurological condition than those with APCR of 38% or less. At the same time, the neurological condition was worse in the patients with APCR of 10% or less than in those with APCR of 15% or more. All patients underwent surgery. The preoperative APCR was compared with the outcomes. The patients with preoperative APCR of 15% or more improved after the operation, but the degree of recovery varied considerably from case to case. The patients with preoperative APCR of 10% or less remained unchanged postoperatively.

Adult↗

Auditory middle latency responses in patients with intracranial space-occupying lesions.

Auditory middle latency responses (MLRs) and auditory brainstem responses (ABRs) were investigated pre- and postoperatively in three patients operated on of intracranial tumor (craniopharyngioma in cases 1 and 2, left-temporal cystic astrocytoma in case 3). In each case examined, preoperative MLRs were informative in evaluating the damage to supratentorial neural structures owing to the tumor; furthermore, they allowed a precious evaluation of the functional integrity of these structures after surgery. Likewise, in case 2 the ABRs indicated a brainstem injury secondary to overzealous manipulation of the right temporal lobe. Finally, in case 3, the most prominent complex of the MLRs, ie Na-Pa, was abnormal both before and after intervention; indeed, in pre- and postoperative MLRs, Na could be identified in both ears, whereas Pa was greatly reduced in amplitude or absent: this finding would seem to suggest that Na and Pa have different generator sites.

Adolescent↗

[Subarachnoid hemorrhage of unknown etiology: management, prognosis, and predictive factors].

Thirty-nine consecutive patients with subarachnoid hemorrhage (SAH) of unknown etiology were studied retrospectively. A significant relationship between arterial hypertension, blood on CT and angiographic spasm was found. The use of nimodipine was associated with a reduction of vasospasm. Antifibrinolytic agents did not increase the risk of ischemic complications. The prognosis was generally favorable.

Cerebral Angiography↗

[The role of inflammatory infiltrate as a prognostic criterion in cerebral metastases. Preliminary results].

Data concerning a preliminary study on the prognostic significance of inflammatory infiltration in cerebral metastases are reported. Seventeen cases of operated cerebral metastases have been studied to investigate their histotype and grade of necrosis, stromal reaction, and inflammatory infiltration. Finally, the results obtained are discussed in relation to the postoperative survival rate of the patients.

Brain↗

Transient occlusion of intracranial blood vessels. Presentation of one clinical and preliminary considerations.

The authors suggest that some cerebral ischaemic lesions depend upon a transient obstruction of intracranial blood vessels (particularly the trunk and the branches of the middle cerebral artery). This explains (as in the patient described here) the cases in which an ischaemic lesion does not correspond with the vascular lesions found on arteriography and/or at autopsy. Furthermore the authors indicate the importance of blood flow in the spontaneous relief of obstruction which is favoured by an undamaged vascular bed. Consequently they recommend, if possible, early surgical treatment of the carotid lesions, in order to reduce the risk of emboli and to improve cerebral blood flow in general.

Adult↗

[Supratentorial arachnoidal cysts].

The AA., after having examined the various hypothesis reported in literature about the etiopathogenesis and the contrasting anatomical and pathological data concerning the arachnoid supratentorial cysts, point out the remarkable frequency of they malformative and above-all post-traumatic genesis. On the formation mechanism of this last type, they agree upon the supposition expressed by Taveras and Ransohoff in 1953. The AA., therefore, after having analysed the principal morphological and topographical aspects, pay attention to the present diagnostic possibilities, above all in radiological range, where the TAC represents, by this time, the examination of election compared with traditional assurances with means of contrast. It follows the analysis of the personal casuistry, consisting in 6 arachnoid supratentorial cysts, two of which clearly post-traumatic and two, very probably, of malformative genesis (for the coexistence of data in favour of both suppositions). The AA. draw these conclusions: the CT Scan is the only diagnostic means which permits an exact pre-operating diagnosis on the nature of the lesion; the surgical and, above all, anatomo-pathological reports assume an essential rule for an exact etiopathogenetic interpretation of the lesion examined.

Adolescent↗

Intracerebral haemorrhage: an attempt at statistical assessment for operability.

A series of 88 patients, who underwent operation for intracranial haemorrhage, is reported. The outcomes are assessed in order to evaluate the operability in relation to the patient's age, the type of onset, the site of haemorrhage, the conscious level, the interval between accident and operation, cardiovascular disease and the dysmetabolic values. A numerical value has been assigned to each factor considered; than the correspondence between these values and the importance of each factor in relation to the clinical state has been analysed. The authors finally point out that their study, although it has a merely indicative significance, agrees sufficiently with the clinical results, as to give a useful pattern for a statistical approach to the question of intracerebral haemorrhage, offering in the meantime hopeful aids to diagnosis.

Age Factors↗