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Biomedical subjects

L V Potashov

Publications and source records attributed to L V Potashov.

At least 37 records · Page 2Linked to original sources

[Substantiation of differential approach to surgical treatment of duodenal ulcer].

An examination of 395 patients with ulcer disease of the duodenum was made. The authors have developed a program of examination of patients with ulcer disease. In addition to traditional methods it includes such methods as intragastric pH-metry in the body and antral part of the stomach, measuring tissue blood flow in the wall of the stomach and duodenum, investigation of parameters of local resistance of the mucosa, medicamentous tests. The possibility to predict curative effects of surgical procedures is discussed.

Adult↗

[Surgical tactics in non-toxic nodular goiter].

Surgical policy in 246 cases of nodular euthyroid goiter was reviewed. Urgent histological examination of operative biopsy specimens of the removed thyroid tissue has disclosed subclinical thyroid cancer in 6.6% of the patients. The authors hold that surgical intervention is an effective measure in prophylaxis and early detection of thyroid cancer in clinical cases of nodular nontoxic goiter.

Adult↗

[Late results of combined surgery of the veins and lymphatic vessels in patients with chronic lymphovenous insufficiency of the leg].

An analysis of long-term results of treatment of 1258 patients with chronic lymphovenous insufficiency of lower extremities has shown the necessity of differentiated approach to different categories of the patients. A substantial improvement of results of the treatment of patients with complicated forms of varicose disease is observed in combination of operations on the venous and lymphatic systems. The character of these operations (lymphovenous anastomoses, lymphonodovenous anastomoses) must be determined strictly individually on the basis of an analysis of clinical course of the disease, data of lympho- and phlebography.

Anastomosis, Surgical↗

[Pathogenetic basis of the diagnosis and treatment of lymphedema of the lower extremities].

A combined clinico-morpho-physiologic investigation was conducted in 98 patients with primary and secondary lymphatic edema. All patients underwent lymphography by means of electron and light microscopy; biopsy specimens obtained from a lymphatic vessel at lymphography were investigated histologically, and contractility records were made. Pronounced disorders were demonstrated in the lymphatic vessels and their myocytes. New rational schedules of pathogenetic treatment for lymphedema of the lower limbs are outlined on the basis of the reported findings.

Adolescent↗

[Repeated operations on the extrahepatic bile ducts].

Experience in repeated operations on the biliary tract in 51 patients is analysed. Endoscopic retrograde cholangiopancreatography is one of the informative methods. The choice of the method of operative treatment must be individualized according to the nature of the pathological process in the biliary system. An endoscopic intervention may be an alternative to surgical operations in many cases.

Adult↗

[Blood flow in the gastric and duodenal mucosa in peptic ulcer].

By means of a polarographic method, the decrease in the rate of blood flow in the gastric and duodenal mucosa at the period of exacerbation of ulcer disease, and its normalization at the period of ulcer healing were revealed. The role of the impaired blood supply of the mucosa in ulcer formation is discussed.

Adult↗

[Diagnostic value of determining endogenous proteinase inhibitors in cancer patients].

Patients with stage III and IV cancers of different sites revealed a 47-76% increase in serum total antitrypsinic activity. A mean 40% increase was observed in cases of inflammatory pathology. Both study groups demonstrated raised alpha 1-antitrypsin levels, while that of alpha 2-macroglobulin did not show any significant changes. The level of alpha 1-antitrypsin accounted for 89 and 83% of total antitrypsinic activity in cases of inflammation and controls, respectively, while in cancer patients this index was significantly lower (70%). The diagnostic value of total antitrypsinic activity appeared to be higher than that of alpha 1-antitrypsin level determination. It is inferred that, apart from alpha 1-antitrypsin, malignant growth is associated with raised levels of more specific endogenous proteinase inhibitors, except alpha 2-macroglobulin.

Clinical Enzyme Tests↗

[Removal of bile stones using a cast].

Experimental studies and clinical observations show that cholangiolithectomy with the help of moulds of fibrinogen and thrombin is an effective method of sanitation of bile ducts.

Adult↗