Search PubMed⌕ Search

Biomedical subjects

L Tibbling

Publications and source records attributed to L Tibbling.

102 records · Page 6Linked to original sources

Esophageal dysfunction in patients with contact ulcer of the larynx.

Vocal abuse is the best-known etiological factor in contact ulcer. Other factors, such as hiatus hernia and gastroesophageal reflux have been discussed. A 12-year study of 58 male patients (mean age 52 years) with present or previous contact ulcers, is reported. Forty-three patients were investigated with esophageal function tests, ie, esophageal manometry including pH monitoring, acid-perfusion test, and acid-clearing test. Esophageal dysfunction was found in 74% which is significantly higher than the 30% found in the general population.

Adult↗

Radiologic findings after fundoplication compared with a pH reflux test and symptoms.

In a follow-up after fundoplication, 61 patients underwent a double contrast examination of the stomach and a radiologic examination to detect any gastro-oesophageal reflux. The radiologic findings were compared with pH reflux test and symptoms. Gastro-oesophageal reflux was found in 7 patients at radiologic examination. None of these patients had an adequate fundoplication at a double contrast examination of the stomach and all had symptoms indicating reflux. Recurrence of gastro-oesophageal reflux may be shown at the radiologic examination and predicted by the morphologic appearances at the double contrast examination.

Deglutition Disorders↗

A simple device measuring differences in level in the oesophagus.

A device for measuring the difference in level between the pressure transducer and a point of measurment is described. It can be used in oesophageal manometry with waterfilled catheters to measure and compensate for superimposed hydrostatic pressure. The practical application of the method is illustrated.

Catheterization↗

Radiologic diagnosis of gastro-oesophageal reflux.

In 149 patients, a standardized radiologic method for the detection of gastro-oesophageal reflux was applied and compared with the results obtained at endoscopy and by a manometric reflux test. Radiologic reflux was recorded in 53 patients, of whom 25 had reflux without abdominal compression and 51 with compression. At least one of the other two types of examination disclosed pathologic conditions in all but 2 of 53 patients. Oesophagitis was significantly more severe among the patients with reflux observed at radiography. The presence of hiatal incompetence with reflux only to the hiatal hernia but not to the oesophagus was not a strong indicator of gastro-oesophageal reflux disease. Hiatal hernia was present in a significantly larger number of the patients with reflux at radiography than in those without reflux. Increased width of the hiatus gave stronger evidence for reflux disease than in patients with a normal hiatus. Thus, the width of the hiatus also had a bearing on the diagnosis of gastro-oesophageal reflux disease.

Adult↗

Radiologic diagnosis of gastro-oesophageal reflux. Comparison of barium and low-density contrast medium.

It has been proposed that the high density of ordinary barium suspensions may complicate the radiologic diagnosis of gastro-oesophageal reflux. For this reason P-contrast was developed (Ferring AB); a contrast medium with the same density as water (1 g/cm3). A comparison of P-contrast and barium (Mixobar Ventrikel 400 mg/ml) was performed in 82 patients. All patients were examined with both contrast media and the findings were compared with those at reflux test at manometry, endoscopy and 24-hour pH monitoring. Another 40 patients and 15 symptom-free controls were examined with two different amounts of barium, 100 ml and 200 ml, to study if the radiologic diagnosis of reflux varied with the volume of contrast medium administered. P-contrast was found to have no advantages over barium for the diagnosis of gastro-oesophageal reflux. The outcome of the radiologic examination was not influenced by the different volumes of barium used.

Barium↗

Radiologic diagnosis of gastro-oesophageal reflux by means of graded abdominal compression.

The aim of the study was to ascertain whether abdominal compression by a standardized technique increases the reliability of the radiologic diagnosis of gastro-oesophageal reflux. Eighty-eight patients were examined by means of a manometric reflux test, 24-hour measurements of pH and endoscopy. The radiologic examination was performed with and without graded abdominal compression, the patient at the same time turning from side to side. When abdominal compression was included the result of the radiologic examination was positive in 31 patients. In the absence of abdominal compression reflux was detected in 11 of these patients. In one patient reflux was detected only without compression. All these 31 patients had one more test positive and in 27 at least 2 more tests were positive. Another 21 patients had reflux disease as indicated by at least 2 of the 3 other tests. The compression technique seems to yield no false positive responses, and proved to be significantly more reliable than examinations without compression.

Abdomen↗

Characteristics of the autonomic response in the visually evoked reflex in humans.

This study aimed (a) to investigate the effect of the visuogenic reflex on the skin microcirculation of the hand and foot, and (b) to compare it to that evoked by thermal stimuli. Fifteen volunteers took part in this study. The laser Doppler technique was used for measuring blood flow (BF). The results showed that a flash of light with a duration of 300 ms caused a significant decrease in BF (mean 38.4 +/- 14.8%) in 10 out of 15 subjects in the hand but not in the foot. The latency was 5.05 +/- 0.7 s and the duration 7.2 +/- 1.8 s. The reaction did not show a significant change when a longer stimulus of 14 s was applied. Repetitive stimuli evoked habituation (p < 0.01). There is significant difference (p < 0.01) between autonomic responses to visuogenic and to calorically evoked reflexes.

Adolescent↗