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Biomedical subjects

L Thomsen

Publications and source records attributed to L Thomsen.

44 records · Page 3Linked to original sources
PubMed1982

Biliary control of beta-glucuronidase activity in the luminal contents of the rat ileum, cecum, and rectum.

The effect of bile exclusion on intestinal beta-glucuronidase activity was studied in the rat. Bile exclusion dramatically decreased the bacterial beta-glucuronidase activity in the cecum and rectum but did not affect the normal low level in the ileum. Thus, bile flow may be the most important factor in modulating beta-glucuronidase activity in the rat large bowel. Dietary substances which can alter bile flow may thus have effects on intestinal bacterial beta-glucuronidase activity. Effects of diet on colon cancer might therefore be explicable in terms of altered bile flow rather than altered bacterial beta-glucuronidase induction.

Animals↗
PubMedDate not supplied

Bronchodilator effects of terbutaline and theophylline alone and in combination in patients with chronic obstructive lung disease.

Thirteen patients with severe partially reversible chronic obstructive lung disease received long-term treatment with a sustained-release preparation of theophylline and a beta 2-agonist (terbutaline) alone and in combination. Combination therapy induced significantly greater bronchodilation than treatment with terbutaline alone in the recommended dose. In 9 out of 13 patients the peak flows were higher during combination therapy than during theophylline treatment alone, but this did not reach statistical significance. Only mild side effects were observed.

Adult↗