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Biomedical subjects

L Svanberg

Publications and source records attributed to L Svanberg.

At least 37 records · Page 2Linked to original sources
PubMed1983

Hygiene for the newborn--to bath or to wash?

Appropriate skin care of newborns is performed partly to prevent infection but also for aesthetic and cleansing purposes. Skin care should involve cleansing with a non-toxic, non-abrasive neutral material. This study compared the relative risks and benefits of washing versus bathing with regard to bacterial colonization rate, clinical infection rate, body temperature and crying. The results confirm our clinical impression that bathing and washing routines do not differ with regard to signs of infection or other clinical complications. However, the washing routine does increase the babies heat loss and make them less comfortable.

Bacterial Infections↗
PubMed1983

Neonatal chlamydial eye infection: an epidemiological and clinical study.

Neonatal chlamydial eye infection was detected in 39 cases of 281 infants with purulent conjunctivitis seen at the Department of Ophthalmology. Most cases of neonatal chlamydial eye infection (90%) were detected during the first month of life, and no case was found after 2 months of age. C. trachomatis was not isolated from any of 161 healthy control infants at 3-4 weeks of age. Genital chlamydial infection was demonstrated in 50% of the mothers to infected infants. Two of these women developed post-partum complications possibly due to chlamydial infection. Mothers of infected infants tended to be younger than average. Of 23 cases examined 2 years later, late sequelae were identified in 3.

Adolescent↗
PubMed1983

Teenage deliveries in a Swedish population in the 1970's.

The investigated material consists of all teenage deliveries in the city of Malmö, Sweden, during the 1970's. For the years of 1972 and 1976, before and after the new abortion act in Sweden, a more detailed study of the pregnancy and delivery has been performed. The study shows that the frequency of adolescent deliveries decreases by about 30% during the 1970's. However, the teenage proportion of the total number of pregnancies remains still unchanged. The investigation also confirms that there is an increased incidence of preterm delivery and low birth weight babies in teenagers, but in other respects there is no increased risk to mother or child in teenage pregnancy. 82% of the teenage mothers were primigravidae and during the first year after delivery, 10.5% of the teenagers fell pregnant again. This is higher than that in a contemporary abortion material, where the corresponding figure is 6.5%.

Abortion, Induced↗
PubMed1983

Legal teenage abortions in a Swedish population in the 1970s.

The number of teenage abortions increased sharply in the early 1970s but gradually decreased from 1975, in absolute numbers as well as in relation to population figures. Teenage abortions now constitute 15% of the total number of abortions. However, the percentage of teenage pregnancies that are terminated by legal abortion is constantly increasing. As the preservation of childbearing function is of paramount importance in teenagers, a low complication rate is essential. Complications occurred in 7% of the cases studies, and the effects of complications of legal abortion on the later obstetric history are discussed. In 14% of the cases a second pregnancy was also terminated artificially. The repeat abortion rate is discussed, with special reference to the contraceptive method used.

Abortion, Induced↗
PubMed1983

Congenital cytomegalovirus infection: on the relation between type and time of maternal infection and infant's symptoms.

Maternal sera from 45 live-born infants with congenital cytomegalovirus (CMV) infection and 4 cases of legal abortion were analysed for CMV IgG and IgM. The investigation included cases from routine work and prospective studies of unselected infants. The purpose was to elucidate the relation between the maternal type and time of infection and the signs and symptoms of the offspring at birth and follow-up. Serological patterns compatible with primary maternal infection during trimesters I and II, but also with secondary infection (in at least 1 case), were associated with infant sequelae or death. Asymptomatic infant infection was found after primary infection in trimesters II and III and after secondary infection. Virus could not be isolated from some of the fetuses legally aborted due to primary maternal infection in trimester I. Attempts to demonstrate CMV IgM activity as a marker of active infection in sera from early pregnancy (period of legal abortion) were successful in only half of the 10 cases with infant sequelae or death. Symptoms at birth were prognostically serious, but the further course was sometimes uneventful even in infants with neonatal signs of cerebral infection. A few children without initial symptoms developed sequelae (impairment of hearing).

Abortion, Legal↗
PubMed1982

Primary and secondary maternal cytomegalovirus infections and their relation to congenital infection. Analysis of maternal sera.

4 382 new mothers were examined retrospectively with the enzyme-linked immunosorbent assay (ELISA) for IgG activity to cytomegalovirus (CMV) during pregnancy. Some of them were also studied with the indirect immunofluorescence (IIF) test for CMV-IgM antibodies. All the infants had been studied for CMV excretion within the first week of life. Nineteen of them had been shown to be congenitally infected with CMV. 1 218 (28%) women lacked CMV-IgG activity at their first antenatal visit (usually in months III-IV). Fourteen of them seroconverted before parturition (primary infection). Thirteen of the seroconverters were shown to develop CMV-IgM activity. In 6 (43%) cases the primary infection was transmitted to the offspring. The remaining 13 congenitally infected infants were born to mothers with a positive IgM-test at their first antenatal control. Only one of these mothers had a clearly positive IgM-test. She was shown to lack CMV-antibodies before conception (primary infection during the first trimester). Preconceptional sera were obtained from further 4 of the 13 seropositive mothers of congenitally infected infants; all 4 had CMV antibodies before pregnancy (secondary infection during pregnancy). The combined studies of the mothers and infants revealed that 21-63% of the congenital infections could have been caused by secondary maternal infections. Prospectively performed, the study would only have disclosed one of the three fetal CMV infections that resulted in neurological sequelae.

Antibodies, Viral↗
PubMed1981

Urokinase-like plasminogen activator as a marker of endometrial neoplasia.

Urokinase-like plasminogen activator (ULPA) was determined with a radioimmunoassay in uterine aspirates from 67 patients prior to curettage. In women with normal endometrial histology the mean concentration of ULPA was 5.4 +/- 2.5 microgram per liter. Only one of this aspirates contained more than 8 microgram per liter. In cases with malignant histology ULPA was above this level in 10 of 11 with a mean concentration of 31.2 +/- 31.4 microgram per liter. In cases with glandular cystic hyperplasia and/or adenomatous hyperplasia 6 of 15 had values above 8 microgram per liter with a mean of 10.3 +/- 6.1 microgram per liter. In addition to other parameters of malignancy such as cytology, detection of ULPA in uterine fluid might prove useful in screening examinations for endometrial neoplasia.

Female↗
PubMed1981

The incidence of primary dysmenorrhea in teenagers.

By means of a questionnaire we studied the menstrual patterns of 502 adolescent girls aged 10--19 years in 1979. The incidence of occasional or consistent primary dysmenorrhea was 43%. The incidence of dysmenorrhea increased considerably with increasing age and the interval between the menarche and the onset of dysmenorrhea was less than one year in 72% of subjects investigated. The occurrence of severe dysmenorrhea resulting in absence from school varied between 8 and 18% in various age groups.

Adolescent↗
PubMed1981

Pregnancy and parturition in a patient with severe Glanzmann's thrombasthenia.

A 35-year-old woman with severe Glanzmann's thrombasthenia became pregnant involuntarily. As a late abortion might cause a bleeding as severe as a delivery, legal abortion was not considered indicated. Treatment with ordinary platelet concentrates was not considered since even HLA-matched platelets did not enhance the platelet function, measured as the aggregability of transfused platelets. This inability was thought to indicate that the patient might have developed antibodies against one of the glycoproteins deficient in this disease. A delivery per vaginam was then preferred because of the local compressing effect. Spontaneous delivery occurred at the end of the 42nd week of pregnancy. The patient delivered a boy with transient thrombocytopenia, probably due to maternal antibodies. To stimulate the haemostasis, uterine contracting drugs were used in unusually large doses and for a relatively long period of time. Tranexamic acid was also given. No haemorrhagic complications could he observed during the puerperium.

Adult↗
PubMed1981

Maternal and infantile infection with Chlamydia in a Swedish population.

Chlamydia trachomatis was isolated from 2.4% of 1 328 puerperal women. The frequency was highest in the age group below 20 years and thereafter decreased with increasing age. Chlamydial conjunctivitis was confirmed in 0.4% of the infants. Two additional cases of conjunctivitis occurred among the exposed infants but chlamydia cultures were not obtained. In a separate ophthalmological material of neonatal conjunctivitis a third of the cases developing within the first month of life was associated with chlamydia. The early and sharp incidence peak for chlamydial conjunctivitis suggested that transmission occurred at delivery. No cases of chlamydial pneumonia were noted. Peroral chemotherapy is recommended in infants for systemic eradication of C. trachomatis.

Adult↗
PubMed1981

Effects of estrogen deficiency in women castrated when young.

In earlier studies on the effects of castration, most of the women had been operated on late in the reproductive period of life. In the present material all the 142 women had been oophorectomized between the ages of 15 and 30 years because of advanced salpingitis. Not only the tubes but also the ovaries had been radically removed. The series was analyzed in respect of causes of death, survival, morbidity, osteoporosis and hormonal state. Complete oophorectomy was found to be followed by (i) a significant increase in the frequency of coronary heart diseases; (ii) an increase in serum cholesterol and triglyceride levels, most significantly in those aged below 60-65 years; (iii) an increase incidence of fractures; (iv) in increased frequency of nervous disorders of psychological rather than endocrinological origin.

Adult↗