Biomedical subjects

L Stockinger

Publications and source records attributed to L Stockinger.

At least 37 records · Page 2Linked to original sources

PubMed1976

[Electronic quantification of experimental hepatic lesions demonstrated by histology (author's transl)].

Explore the source record for details and available documents.

Animals↗

PubMed1976

[Fat resorption: current concepts and micromophology].

Recent concepts in the physiology of intestinal fat absorption are reviewed and the intraluminal formation and the role of the mixed lipid micelle, the concept of the unstirred water layer and the role of the fatty acid binding protein in the intracellular transport of long chain fatty acids are particularly emphasized. It is pointed out that only little information is available on the exact mechanism of the synthesis of intestinal lipoproteins and their export from the intestinal epithelial cells. Finally, preliminary results are presented of an electron-microscopical investigation of the intestinal mucosa of rats at different intervals after intraduodenal injection of an emulsion of lipids.

Animals↗

PubMed1975

[Some aspects of biological membranes: concepts and techniques (author's transl)].

Some of the abundant data on the structure of biological membranes are compiled in this short review, with particular emphasis on morphological techniques. The "fluid mosaic" model of biological membranes has rapidly gained importance as the fundamental concept. According to this model, protein particles swim in a lipid bilayer, whose molecules are ordered with their hydrophilic end outside and their hydrophobic tail inside the membrane. Proteins are spatially stabilized and actively moved by a submembranous net of fibrillar proteins. Information about the orientation of protein molecules within the bilayer is obtained by protein labelling with membrane impermeable compounds and subsequent gel-electrophoretic separation of the solubilized components. Freeze etching brings to light intramembranous particles which are probably segments of the membrane proteins that stand out from the plane of the split hydrophobic membrane interface. By this method the morphology of cell contacts, for example, can be analyzed and comprehended at a supramolecular level. Special techniques such as observation of both matching sites of the split membrane halves or deep etching (whereby the actual surface of membrane is exposed) may provide further valuable contributions to the rapidly expanding field of membranology.

Basement Membrane↗

PubMed1975

The reaction of connective tissue fibers in the tumor of Recklinghausen's disease.

The structure of connective tissue fibers in cutaneous neurofibroma was investigated by normal transmission electron microscopy and by the electron microscopic dark field method. Elastic fibers were found in the periphery of the tumor nodules. Proceeding towards the center of the tumor the elastin content of the fibers diminished leaving at least a microfibrillary bundle. The collagenous fibrils normally had a diameter of 300-400 A. Only in the periphery of the tumor thick collagenous fibrils (700-800 A) comparable with those of the normal skin could be detected. In the vicinity of nerve fascicles in the tumor, numerous banded structures, so called "Luse bodies" were found.

Collagen↗

PubMed1975

[Catabolic processes in the rectal mucosa. Light and electron microscopic studies].

The phagocytosing activity of macrophages and fibrocytes of the lamina propria was examined by means of light and electron microscopy; the material had been obtained through 121 biopsies performed on patients ranging in age from 3 weeks to 43 years (113 taken from the rectum, 8 from the small intestine). The phagocytosing activity of the stroma has been known since the studies of v. Möllendorf, Clara, Patzelt, Maximov, Malatzkaya carried out on guinea pigs, rats, birds and a few human embryos. In recent years this problem has been raised again by some American authors. Our studies close the gap existing for the age group ranging from birth to the 16th year. It was demonstrated that the rate of this activity is much higher than hitherto assumed by Askar, Ekuan and Hill, Azzopardi and Evans. The authors discuss the reasons for these discrepancies in the finding, and the origin and composition of the substances ingested.

Adolescent↗

PubMed1975

[Clinical and morphological features during the course of Whipple's disease(author's transl)].

Clinical and histological characteristics of Whipple's disease have been described extensively by various authors, but there are only few reports about repeated documentation of clinical and especially of micromorphological features during the course of the disease. We therefore report a case who was followed closely over a period of 3 years; small bowel biopsy was performed on 6 occasions during this time. Antibiotic therapy brought complete recovery from the disease and was followed by the disappearance of bacillary bodies in the lamina propria of intestinal mucosa. Despite this, many macrophages containing the typical PAS-positive material could still be demonstrated. The development of macrophages as well as etiologic aspects of the disease are discussed.

Adult↗

PubMed1974