A lumped parameter model of the cerebrospinal fluid system.
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Biomedical subjects
Publications and source records attributed to L Stark.
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The consensual response of the pupil in the cat was driven by means of a light flux impinging on the contralateral retina. Spike trains recorded extracellularly from single units in the midbrain show correlation with the concurrently recorded pupil area. The temporal dynamics found confirm two earlier studies of sinigle-unit responses and quantitative nerve stimulation. Both of these indicate that most of the 200-millisecond transport delay resides in the neuromuscular apparatus. Neurons whose activity correlated either with constriction with dilatation phases of Change in the pupil area were observed.
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A hand control model is proposed. Investigation of the hand's intermittency synchronization shows it corresponds to an input-synchronized sampler rather than the clock-synchronized sampler more typical of engineering systems. A velocity control mechanism, similar to that in an eye tracking system is shown to be absent in the hand. A quantitative transfer function for predictable inputs serves further to define the hand's input adaptive characteristics. Stability margin adjustments of a linear reduced model enabled us to match the available quantitative data. The most exciting result of this study is the evidence for intermittency: a refractory period shown in the short pulse experiment, peaks in the frequency response experiments, and a saccadic sequence of steps in response to an open loop step input and to a closed loop ramp input.
Using a piecewise linear approach, individual saccadic eye movements have been Fourier decomposed in an attempt to determine the effect of saccadic amplitude on frequency characteristics. These characteristics were plotted in the traditional Bode plot form, showing gain and phase as a function of frequency for various eye movement amplitudes. Up to about one octave beyond the -3 db gain frequency, the limiting system dynamics represented by the saccadic trajectory of a given amplitude may be considered linear and second order. The -3 db gain frequency was used as a measure of bandwidth, and the -90 degrees phase crossover frequency was used as a measure of undamped natural frequency. These two quantities were used to calculate the damping factor. Both bandwidth and undamped natural frequency decrease with increasing saccadic eye movement amplitude. The damping factor shows no trend with amplitude and indicates approximate critical damping. When compared with the normal variation of characteristics for a given movement, the frequency characteristics of fixed-amplitude saccades showed no generalized trends with changes in direction or DC operating level of movement.
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