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Biomedical subjects

L Soto

Publications and source records attributed to L Soto.

40 records · Page 3Linked to original sources
PubMedDate not supplied

Systemic vasculitis associated with Fasciola hepatica infection.

We report the case of a 50-year-old man who presented with systemic vasculitis associated with Fasciola hepatica infection. The patient presented with severe skin, kidney, spleen, ophthalmic, and neurological compromise. An immunological examination for primary vasculitis was negative and other infections were discounted by microbiological and serological analyses. The patient was treated with steroids without clinical response. The Fasciola hepatica infection was confirmed by the presence of specific immunoglobulin G (IgG) serum antibodies detected by a quantitative enzyme-linked immunosorbent assay (ELISA) with an optical density (OD) of 0.483 OD units (normal value<0.170 OD units) and a high-titre complement fixation (1/80 dilution). The patient received treatment with triclabendazole and all symptoms and systemic manifestations resolved within weeks. Hence, this previously unreported vasculitis-associated infection, if identified opportunely, can be treated and cured.

Animals↗
PubMedDate not supplied

[Seroprevalence of delta infection in a group of patients with HBsAg positive in the city of Maracaibo].

In order to establish a preliminary information about the penetration of delta infection in our population, 40 HBsAg positive sera were tested for antidelta. 20 were asymptomatic patients and 20 were symptomatics. In the group of asymptomatic patients 3 belong to a high risk population: 1 homosexual, 1 dialysis patient, 1 nurse of dialysis unit. None of the patients of this group were positive for antidelta. In the group of symptomatics one was positive for antidelta. It's represents a seroprevalence of 5%. This patient was an indian who lives in the city but was born in Perijá where severe epidemics have been reported. These results support that the infection seems to be restricted to this indigenous group but the spread must be considered because the patient was living in the city. In addition, the use of antidelta as the unique serologic marker should undervalue the real prevalence of infection in the cases of acute hepatitis, which represent the majority of symptomatics patients. In consequence the paper of delta agent must be considered in the genesis of hepatitis in our population as well as its further epidemiologic course.

Adolescent↗