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Biomedical subjects

L Seipel

Publications and source records attributed to L Seipel.

At least 235 records · Page 13Linked to original sources
PubMed1979

[The clinical relevance of intraoperative electrophysiologic mapping (author's transl)].

Electrophysiological intraoperative mapping is described as a technique for identification of the specialized AV conduction system during open heart surgery; furthermore it is suitable for delineating the morphological origin of ventricular tachycardias which requre surgical therapy. The mapping technique is described with respect to its methodical aspects and illustrated by means of congenital and acquired heart disease.

Bundle of His↗
PubMed1979

Surgery of life-threatening ventricular tachyarrhythmias associated with ventricular aneurysm.

In 11 patients with left ventricular aneurysm and ventricular tachyarrhythmia unresponsive to conventional antiarrhythmic therapy surgical treatment was performed by resection of the aneurysm. One patient underwent epicardial electrophysiological mapping intraoperatively, and the site of earliest activation during tachycardia was established. One patient did 11 hours postoperatively. Three patients are cured from their tachycardia 3 to 22 months after surgery. Six patients have still persistent premature ventricular beats which are now controlled satisfactorily with antiarrhythmic drugs. Our results demonstrate the therapeutic value of aneurysmectomy in the treatment of related ventricular tachyarrhythmias. The practical relevance of intraoperative electrophysiological mapping procedures for localizing the origin of ventricular tachyarrhythmias is a subject which merits further discussion.

Adult↗
PubMed1979

Intraoperative electrophysiologic mapping during cardiac surgery.

Intraoperative mapping is a method to document the surgical anatomy of cardiac tissues with electrophysiologic importance cartographically at time of surgery. The presented communication gives a survey of the present status of the technique of electrophysiologic mapping and its essential clinical applications. Special attention in this regard is directed to the intraoperative identification of the specialized AV conduction system in congenital cardiac malformations with unpredictable location of His bundle, to the detection of accessory AV bundles in patients with the Wolff-Parkinson-White syndrome and to the intraoperative morphological study of ventricular reentry tachycardias. Suitable technical equipment for "clinical" intraoperative electrophysiologic mapping is described in detail.

Cardiac Surgical Procedures↗
PubMed1979

[Electrophysiological mapping during open-heart surgery (author's transl)].

Intraoperative electrophysiological mapping provides a method to identify the specialized atrioventricular conduction system and to localize the morphological origin of different tachycardiac rhythm disorders at time of surgery. The basic technical aspects and methodical implications are presented with respect to its clinical applications.

Atrioventricular Node↗
PubMed1979

[Arrhythmias in patients with mitral valve prolapse syndrome. An echo- and electrocardiographic study - (author's transl)].

The echocardiograms and electrocardiograms of 76 patients with mitral valve prolapse syndrome (MVP) were examined and compared with those of 20 normal subjects. 30 patients had a late systolic, 32 a holosystolic MVP, 14 patients had a mixed motion pattern of the MVP. Eighty percent of them had arrhythmias, which were detected in 44% only by 24-hours ECG, in 32% by 24-hours ECG and exercise ECG and in 4% only by exercise ECG. 16% of the patients had only atrial premature contractions (APC), 22% only ventricular premature contractions (VPC), 39% had both ventricular and atrial premature contractions. Multifocal VPC'S WERE MORE COMMON IN PATIENTS WITH LATE SYSTOLIC MVP, salvos of VPC however were detected in 3 patients with holosystolic and in one patient with late systolic MVP. Only less severe arrhythmias, in general isolated, univorm VPCs were found in 40% of the normal subjects.

Adolescent↗
PubMed1979

[Cardiac surgery in the 7th and 8th decade (author's transl)].

Progress in cardiovascular surgery and the growing amount of older people made it possible and necessary to extend open-heart-surgery to patients between 60 and 75 years of age. From 1970 to 1978 174 cardiac procedures (mostly for valve replacement and aorto-coronary-vein-bypass) were performed in this group of older patients. The total mortality rate was 18.3%. These results which have to be improved in several areas demonstrate clearly that surgery is of real benefit for these older, properly selected patients; the operative risk seems to be acceptable.

Aged↗
PubMed1978

[Severe mechanical haemolysis after correction of a partial atrioventricular canal (author's transl)].

Following correction of a partial atrioventricular canal and closure of the atrial septum defect with a Dacron patch a severe hemolytic anemia developed caused by moderate mitral insufficiency. The clinical postoperative course and the successful treatment by reoperation is described in detail. The Dacron patch was excised, the mitral cleft was closed by four single sutures, and the septal defect was covered with a pericardial patch. In the literature ten other communications were gathered reporting hemolytic anemias following correction of endocardial cushion defects with Dacron, Teflon, or Ivalon patches. Three of six reoperated patients died postoperatively. A woman died after correction with renal failure caused by severe hemolysis. In four patients hemolytic anemia was compensated and there was no need for reoperation. In consideration of our own experience and those reported in the literature we recommend pericardium instead of synthetics for closure of atrial septum defects of Foramen-primum-type.

Anemia, Hemolytic↗
PubMed1978

Prognosis and possible presymptomatic manifestations of congestive cardiomyopathy (COCM).

In order to find evidence of prognosis and of presymptomatic manifestation of congestive cardiomyopathy (COCM) in fifty-eight patients, the extent of morphological changes of endomyocardial catheter biopsy (EMCB), clinical and haemodynamic data were correlated to the clinical course. In addition, clinical, haemodynamic, angiographic, morphological and His-bundle electrographic studies were performed in patients with left bundle branch block (LBBB), normal left ventricular end-diastolic volume, and normal coronary arteries (n = 43). Related to a 10-year mortality rate of 70% from the onset of symptoms, COCM is one of the most severe heart diseases. Endomyocardial catheter biopsy (EMCB) allowed clear prognostic separation in patients with COCM and seems to be of diagnostic value in patients with only slightly enlarged hearts and in patients with a short history of symptoms. The studies also revealed much evidence that at least some patients with LBBB, normal left ventricular end-diastolic volume (LVEDV) and normal coronary arteries exhibit an early stage of COCM. In these patients especially EMCB with severe changes of heart muscle cells and/or impaired left ventricular function may indicate subsequent COCM. So that there is now a new indication for performing EMCB.

Adult↗