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Biomedical subjects

L Schweiberer

Publications and source records attributed to L Schweiberer.

At least 253 records · Page 14Linked to original sources

[Microsurgical aspects of wound healing in the extremities (author's transl)].

Microsurgical operative technique made it possible to restore the arterial and venous blood flow or to improve it, even for a relatively small tissue area, and to re-innervate these fabrics. Reconstruction of lymphatic drainage is technically possible, but quite a number of problems remain to be solved before further clinical application is possible. Grafting of a microvascularly pedunculated bone chip is superior to the bone chip without primary vascularisation, but will offer advantages over grafting of spongiosa in very rare cases only. At the present moment it is not yet possible to safely assess the influence exercised by re-innervation on wound healing.

Animals↗

[Microsurgical plastic reconstruction of the explosion-damaged hand].

During the last two years, 16 severe explosion injuries of the hand have been treated with plastic microsurgery in our hospital. The injury had arisen in seven cases from the mixture sugar + sodium chlorate (C12H22O11 + NaClO3). This substance mixture may already be caused to explode by slight vibrations and the warmth of the hands. In explosion injuries, there is mechanical, chemical and thermal tissue damage. The postoperative course is therefore complicated in almost all cases. However, by meticulous removal of the disseminated foreign particles, excision of necrotic tissue and extensive reconstruction of the interrupted vascular and nerve supply, it is possible in a few cases to preserve functionally important parts of the hand. Later plastic procedures are made more difficult by tissue fibrosis and foreign body granulomas.

Adolescent↗

[Experimental studies of autograft with cancellous bone in the diaphysis of long bone (author's transl)].

The acceptance of fresh autologous cancellous bone in a wedge-shaped diaphysial cortical defect was examined in 2 groups of 5 dogs microangiographically and histologically 1,2,3,4 and 6 weeks after transplantation. The main recanalisation takes place after one week from the medullary canal, two weeks later periosteal vessels are connected and finally three weeks later the tender vessels of the Haversian canal system within the cortex are being integrated. Histologically, after one week active formation of fibrous bone can be seen adjacent to numerous capillaries originating within the medullary canal. Simultaneously, considerable degradation of transplanted trabeculae by mono- or polynuclear osteoclasts takes place. Formation of new bone occurs according to newly built capillaries. After 4 weeks, transplanted trabeculae can be found only sparsely, the new fibrous bone is being remodelled into lamellar bone. After 6 weeks, the entire fibrous bone has been transformed into lamellar bone and is calcified. A trajectorial orientation of the Haversian system according to that of the host cortical bone can be recognized vaguely.

Animals↗