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Biomedical subjects

L Savi

Publications and source records attributed to L Savi.

At least 55 records · Page 3Linked to original sources
PubMed1984

[Lateralization phenomena and headache].

Ipsilateral carotid and vertebral vasomotor phenomena are marked components of a unilateral cluster headache crisis. Investigation of lateralisation at the height of a crisis has shown that Doppler findings supplement Heick's observation of the reversible opening of both intra and extracranial arteriovenous shunts. This observation is in line with personal thermographic evidence and that of Lance indicating local hypothermia, and with Wolff's demonstration of dilatation and congestion associated with the superficial temporal artery. Personal dynamographic findings now point to a local extra-intracranial artery pressure gradient as the cause of the peripheral component of lateralisation in cluster headache.

Arteriovenous Anastomosis↗
PubMed1984

[Serum complement and immunoglobulins in patients with common migraine].

Research has already been conducted into complement, immunoglobulin, and immune complexes with regard to analogies with allergy mechanisms (in the case of dietary headaches) or with vasculitic alterations. The results showed no complement activation or variation in the immunoglobulin of migraine sufferers during healthy intervals and migraine attacks that in any way support an involvement of the immune system in the pathogenesis of common migraine.

Adolescent↗
PubMed1982

[The mechanism of action of biofeedback electromyography in muscle tension headache].

Headache of muscle tension origin and/or with a muscle tension component is underlain by a high degree of head, neck, and face muscle contraction. Biofeedback EMG enables patients to check their muscle tension, and thus achieve complete decontraction. Reference is made to a series of 59 subjects divided in 4 groups in accordance with the number of sessions needed to obtain decontraction. It was found that no relation exists between such number and the degree of improvement obtained. On the other hand, it was not possible to determine whether a relation exists between the moment in which decontraction is achieved and the commencement of an improvement in the symptomatology.

Biofeedback, Psychology↗
PubMed1982

L-carnitine in haemodialysed patients. Changes in lipid pattern.

Carnitine is a selective carrier of free fatty acids from the cytoplasm to the mitochondria. Dialysed patients are chronically and progressively carnitine deficient due to loss in the dialysate. Simultaneously such patients present impaired lipid metabolism and this may provoke varied pathological conditions ranging from isolated hypertriglyceridaemia to frank forms of hyperlipoproteinaemia types IIa, IIb, and IV, and to apparently normolipaemic situations falling within a lipoprotein pattern tending to become pathological with low levels of HDL-cholesterol. In the present investigation we evaluated the effect of l-carnitine (versus placebo) on the lipid pattern in a group of apparently normolipaemic dialysed patients, but with altered coronary risk factors (HDL-cholesterol, beta:alpha lipoprotein ratio). Examinations showed no significant changes at the 15th and 30th day of placebo treatment, whereas the l-carnitine treated group displayed a statistical significant increase in HDL-cholesterol accompanied by reduced pre-beta-lipoproteins and decreased beta:alpha ratio.

Adult↗
PubMed1980

[Observations on lipid metabolism in normal pregnancy and in some pathological pregnancy disorders].

Chemical determination of total and esterified cholesterol and electrophoretic separation of plasma lipoproteins was carried out in a chemico-clinical approach to the pathology of lipide metabolism in pregnancy. In a future study, the investigation will be extended to the neonatal aspect of the problem. 136 women were studied, with 446 samples being taken, specifically: 65 controls, i.e. pregnant women not presenting pathology that might obviously involve lipide metabolism, 36 hypertense pregnant women, 28 diabetic and 7 with gravidic hepatosis. Observation of the data confirms that in pregnancy there is a steady, meaningful increase in cholesterolaemia and that the electrophoretic picture shows a steady reduction in alpha-lipoproteins, with stimulatneous increase in pre-beta proteins, reaching a peak in hepatosis cases, and an increase in beta lipoproteins. All this agrees with functional and teleological modifications in lipide metabolism during gestation.

Adult↗
PubMed1978

Fibrinogenemia, determined immunonephelometrically, as a possible parameter in the evaluation of peripheral arteriosclerotic arteriopathy.

The concentration of plasma fibrinogen increases with age and is particularly elevated in subjects with vascular changes due to atherosclerosis. Fibrinogen, which is the meeting point of the "cascade" of the coagulation factors and an important regulating factor of plasma viscosity, occupies a key position in atherosclerotic vascular pathology. This indicates the necessity to keep its value within normal limits, to avoid the clinical development of the disease or improve its evolution. Thus, frequent checks of the fibrinogenemia are necessary at various ages even if this means a big organizational burden. However, this checking can be facilitated by using automatic techniques, such as the immunonephelometric method, with which it is possible to carry out a large number of determinations in a short time.

Adult↗
PubMed1978

Peripheral vascular dynamics studied by calcium ion inhibition.

The study of peripheral vasomotility through inhibition of parietal smooth muscle cells is of great clinical interest for both diagnostic and therapeutic reasons. It permits the differentiation of the functional clinical forms from the organic. And in organic forms, once any spastic component is eliminated, it determines the site and severity. On the basis of these premises we have developed a test for the study of vascular dynamics based on the use of nifedipine as antagonist of calcium ions.

Adult↗