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Biomedical subjects

L Sanarelli

Publications and source records attributed to L Sanarelli.

24 records · Page 2Linked to original sources
PubMedDate not supplied

[Syringomyelia. Clinical and neurophysiologic correlations (SEP) as a function of surgical treatment].

The authors have studied the somatosensory evoked potential (SEP) behavior following stimulation of upper and lower limbs in two subjects affected by syringomyelia. The patients were evaluated electrophysiologically before and after decompressive surgical treatment. The findings indicate a positive correlation between the SEP recordings and the role of CSF pressure in the central nervous system.

Adult↗
PubMedDate not supplied

[Articulation disorders in aphasia. Considerations in several clinical cases].

Selective deficit of verbal output not associated to other anomalies of language, represents a syndrome in which articulatory as well as linguistic aspects can be independently affected. The critical lesion for pure articulatory deficit appears to involve left prerolandic cortico-subcortical structures. Nevertheless, in relation to individual differences in cerebral organization, damage in these structures can be responsible for a simultaneous deficit of articulatory and linguistic mechanisms.

Aphasia↗
PubMedDate not supplied

Electrophysiological study in patients with chronic hepatic insufficiency.

Twenty patients affected by chronic hepatic insufficiency were studied by means of combined EEG, VEP and BAEP recordings. Subjects were classified, according to Parsons-Smith criteria, in grade 0 (without any clinical sign) and grade I (with minimal mental disturbances). In group 0 patients an elevated incidence of VEP alterations (40%) was observed, while EEG and BAEP recordings were less frequently (10%) abnormal. In group I patients a high degree of EEG (60%), VEP (70%) and BAEP (70%) abnormalities was found. Mean latency and interpeak interval values in group I patients were significantly prolonged if compared with the grade 0 and control groups. No correlations were found between electrophysiological data and blood biochemical parameters examined (ammoniemia, aminoacidemic pattern).

Adult↗
PubMedDate not supplied

[Changes in slow cerebral potentials (CNV) subsequent to midazolam administration. Double-blind study].

The result of a study on the modifications of the Expectancy Wave (or Contingent Negative Variation) induced in 10 cases by a new benzodiazepine, midazolam, is reported. A double blind cross-over comparison with placebo has been carried out. The administration of placebo did not give rise to significative variations of the Expectancy Wave after 10, 30 and 240 minutes. The administration of midazolam was followed by a statistically significative reduction of the amplitude of the area and of the maximum peak of the Expectancy Wave. This effect was manifest after 30 minutes from the ingestion of a 15 mg tablet of the drug. After 4 hours both parameters showed again values similar to those observed in basal conditions. Midazolam thus appears to possess a central activity typical of the benzodiazepines group, which is of an early onset and short duration and could be properly utilized on a clinical ground.

Adult↗