Biomedical subjects

L Saltuari

Publications and source records attributed to L Saltuari.

42 records · Page 3Linked to original sources

PubMed1989

[Motor speech disorder after removal of a glioblastoma in the left hemisphere: Cortical disorder or apraxia?].

A 38-year-old male patient with a deep central parietal lesion in the left hemisphere reveals a motor speech disorder but no aphasia as evidenced by linguistic testing with the Aachener Aphasietest. Nuclear magnetic resonance tomography of the brain shows no lesion of the brainstem. Whether the speech disorder can be termed cortical dysarthria or apraxia of speech is left open to discussion.

Adult↗

PubMed1985

[A special flicker fusion frequency method for detection of the effects of gerontopharmaceuticals exemplified by the L-eburnamonine study].

A clear difference between active drug and placebo is not always found when using the ascending and descending thresholds of the critical flicker fusion test (CFF). We selected a test requiring attention and concentration and performed again the CFF after this 6-minute concentration-test (reactive CFF). This reactive CFF was then used in a double-blind study in 30 ambulant patients with cerebro-vascular arteriosclerosis treated for 8 weeks with 80 mg/day cervoxan or placebo. After the treatment period the reaction of the CFF after the 6-minute concentration-test demonstrated a significantly more frequent improvement of the vigilance in the Cervoxan group compared to the placebo group.

Aged↗

PubMed1983

Klüver-Bucy syndrome in man: experiences with posttraumatic cases.

After the original description of characteristic behavioral changes in rhesus monkeys after bilateral resection of major portions of the temporal lobes by Klüver and Bucy in 1937 [11], similar syndromes have repeatedly been reported in human pathology. The present paper is based on clinical analysis of 40 cases of traumatic apallic syndrome (TAS), 30 of whom developed a complete or partial Klüver-Bucy syndrome during recovery. The dynamics in the development of a Klüver-Bucy syndrome during remission of a TAS are analyzed. The delineation between a pre-stage, full-stage and remission-stage of the Klüver-Bucy syndrome is suggested.

Adolescent↗

PubMed1983

Epilepsies with diffuse slow spikes and waves of late onset.

26 adult epileptic patients with diffuse slow spikes and waves and start of seizures after the age of 6 years were analyzed. The seizure spectrum encompasses generalized and focal seizures. The occurrence of several types of seizures is the rule. Epileptic drop attacks are most characteristic. Atonic, tonic and myoclonic features may be present in this type of seizure. Neurological and mental deficits are common. Compared with Lennox-Gastaut syndrome of children, the degree of intellectual impairment is relatively mild. As to the etiology a primary and a secondary group can be distinguished. Genetic predisposition seems to play a crucial role in the primary group.

Adolescent↗

PubMedDate not supplied

Sleep in the last remission stages of vegetative state of traumatic nature.

Polygraphic studies were carried out on 20 patients (13 male, 7 female, average age 25.3 years) in the last remission stages of a traumatically caused vegetative state (apallic syndrome: stages V-VIII according to Gerstenbrand's classification). The presence of all the stages of NREM and REM sleep was observed in all patients, as was typical spindling activity. With respect to patients in the first remission stages of vegetative state, the total sleep time (TST) was seen to increase as a percentage of the total time in bed (95%) and with respect to TST, the periods of waking after a period of sleep diminished (wake after sleep onset: 9.73%). Stage I decreased (10.39%), while stages II-III-IV increased (32.36%, 4.29% and 6.04% respectively). There was a clear increase in the REM percentage (37.19%); spindling rate and index both increased (4.9/min and 12.1 respectively).

Action Potentials↗

PubMedDate not supplied

Intrathecal baclofen application in patients with supraspinal spasticity secondary to severe traumatic brain injury.

Intrathecal application of baclofen is considered the treatment of choice in patients suffering from spinal spasticity insufficiently responding to conventional oral antispastic medication. This approach has also been used successfully in cases with spasticity of supraspinal origin. To achieve a good therapeutic response in the latter condition the amount of intrathecal baclofen has to be approximately twice the dosage required in spinal spasticity. We report on 8 patients suffering from supraspinal spasticity due to severe traumatic brain injury. Intrathecal baclofen reduced spasticity in all patients (mean Ashworth Score from 3.9 to 1.6; mean Reflex Score from 4.0 to 1.4). In some cases improvement of motor performance and in one case recovery of bladder function were noted. In two patients focal epileptic seizures with secondary generalization seemed to be associated with the application of baclofen. The local intrathecal application of baclofen has proven to be an effective therapy in otherwise intractable cases of severe supraspinal spasticity.

Acute Disease↗