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Biomedical subjects

L S Reisner

Publications and source records attributed to L S Reisner.

28 records · Page 2Linked to original sources

Bupivacaine paracervical block. Effects on the fetus and neonate.

To evaluate effects on the fetus and neonate, 53 paracervical blocks were administered to 38 low-risk parturients using a controlled superficial injection of 0.25% bupivacaine. Continuous fetal heart rate monitoring revealed no instance of bradycardia or late deceleration pattern. Apgar scores, cord arterial and venous pH values, and neurobehavioral evaluations of the neonates were similar to those observed in other low-risk patients. The effectiveness of pain relief of the blocks was less than expected or reported by other authors. Although we observed no harmful effects on the fetus or neonate from the superficial paracervical injection of bupivacaine, we did not find this combination of drug and technique to give dependable, effective pain relief in labor.

Analgesia↗

Expansion of an air-filled subdural space during nitrous oxide anesthesia.

The long-term administration of nitrous oxide anesthesia during craniotomy as well as following closure of the parietal craniotomy flap (under no tension) leads to significant expansion of the residual air bubble trapped under the dura. A case is presented in which an extracerebral avascular space, filled only with gas, caused a marked shift of the intracranial structures and uncal herniation secondary to nitrous oxide anesthesia during craniotomy and postcraniotomy angiography.

Adult↗

[Epinephrine injection with enflurane anaesthesia: incidence of cardiac arrhythmias (author's transl)].

Two hundred patients, primarily A.S.A. status I and II, were prospectively divided into two groups of 100 each. One group received nitrous oxideoxygen-enflurane anaesthesia and subcutaneous infiltration of adrenaline in lignocaine for haemostasis, while the other received enflurane but not adrenalin. Patients were continuously monitored with a cardioscope. Epinephrine dosages were limited to those recommended for safe use with halothane anaesthesia. No patient in the control group experienced an arrhythmia, and only one patient in the study group developed a burst of premature ventricular contractions following adrenaline injection. The authors conclude that adrenaline may be given subcutaneously for hemostasis in patients under enflurane anaesthesia provided the safeguards established for halothane are observed.

Adolescent↗

The frequency of postdural puncture headache in obstetric patients: a prospective study comparing the 24-gauge versus the 22-gauge Sprotte needle.

STUDY OBJECTIVE: To compare the frequency of postdural puncture headache (PDPH) in obstetric patients when using the 24-gauge or the larger 22-gauge Sprotte needle. DESIGN: Prospective, randomized study. SETTING: Four hospitals. PATIENTS: 375 ASA physical status I and II cesarean section and postpartum tubal ligation patients. INTERVENTIONS: Obstetric patients were randomly assigned to receive spinal anesthesia via a midline dural puncture using the 24-gauge or the 22-gauge Sprotte needle. MEASUREMENTS AND MAIN RESULTS: The rate of PDPH was determined by a postoperative visit by the anesthesiologist as well as questioning patients by telephone 1 week or more after discharge. In the 24-gauge Sprotte needle group (n = 186), 2 mild and 1 moderate PDPHs were reported, for an overall rate of 1.61%. In the 22-gauge Sprotte needle group (n = 189), 2 mild and 1 moderate PDPHs were reported, for an overall rate of 1.59%. All headaches except 1 resolved within 72 hours with conservative treatment. One patient from the 22-gauge Sprotte needle group required an epidural blood patch. There were no failed blocks in either group. CONCLUSIONS: Our results suggest that the 22-gauge Sprotte needle, when compared with the smaller 24-gauge Sprotte needle, can be used in obstetric patients without increasing the frequency of PDPH.

Adult↗

Ventricular arrhythmias after epinephrine injection in enflurane and in halothane anesthesia.

The use of subcutaneous epinephrine during anesthesia is a common clinical practice for providing surgical hemostasis. In studies with 100 patients given either enflurane or halothane, with or without subcutaneous epinephrine, the incidence of ventricular ectopy in patients receiving halothane without epinephrine was 3 percent, while in those given epinephrine with halothane, the incidence was 7 percent. Those who received enflurane alone had no ectopic beats, while ventricular ectopy with enflurane and epinephrine resulted in an incidence of 1 percent. The authors conclude that enflurane anesthesia with concomitant administration of subcutaneous epinephrine is safe, provided the safeguards previously established for use of epinephrine with halothane are observed.

Adjuvants, Anesthesia↗