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Biomedical subjects

L S Neinstein

Publications and source records attributed to L S Neinstein.

44 records · Page 3Linked to original sources

Nonsexual transmission of sexually transmitted diseases: an infrequent occurrence.

Sexually transmitted diseases occur in epidemic numbers in the United States today. Nonsexual transmission of these diseases is rarely an issue in adults. However, when the same diseases are found in children, the tendency of pediatricians and other health care practitioners has been to believe the mode of transmission is asexual. A review of gonorrhea, Chlamydia trachomatis, herpes genitalis, condyloma acuminata, Trichomonas vaginalis, syphilis, chancroid, and granuloma inguinale infections has been made to address the issue of nonsexual transmission of sexually transmitted diseases. Nonsexual transmission of these infections is an infrequent occurrence and when they affect the prepubertal child, sexual abuse must be highly suspected.

Adolescent↗

Congenital absence of the vagina.

Congenital absence of the vagina is the second leading cause of primary amenorrhea. Three patients had Mayer-Rokitansky-Küster-Hauser syndrome or congenital absence of the vagina. We discuss the clinical, diagnostic, psychosocial, and therapeutic features of these patients and the syndrome. The lack of diagnosis until after puberty of this syndrome in many patients demonstrates the need for more careful genital examination in prepubertal and pubertal girls.

Adolescent↗

Menstrual dysfunction in cystic fibrosis.

Several factors potentially involved in the menstrual dysfunction of some females with cystic fibrosis were analyzed by a retrospective chart review. The mean age of menarche for the cystic fibrosis patients was 14.4 years, compared to 12.9 years for American females (p less than 0.001). At last evaluation, comparison of the mean figures for amenorrheic patients and for menarchal cystic fibrosis patients reveals statistically significant differences in the age of diagnosis, weight-height index, weight, height, percent of body fat, weight percentile, and height percentile. The highest correlative was weight (r = 0.59). Of our cystic fibrosis patients who were menarchal, 95% had a weight greater than 82 pounds, whereas 75% of those who were amenorrheic weighed less than 82 pounds. Menstrual irregularities, sexual activity, and contraceptive use among these patients also is discussed.

Adolescent↗

Hypnosis as an adjunct therapy for asthma: case report.

This study reports the effect of hypnotherapy in an asthmatic. The patient had moderately severe asthma with frequent attacks despite multiple medications. He received four weekly hypnosis sessions, and was then followed bimonthly for a year. The patient's course was followed by subjective daily scoring of wheezing severity, daily recording of peak expiratory flow rate by a Wright minispirometer, and once a month recording of his Forced Vital Capacity (FVC), Forced Expiratory Volume in one second/Forced Rate (MMRF). The severity rating showed improvement at one year when the start of therapy was compared to pretherapy (P less than .005). The daily peak flow rate averaged 486 liter/min before starting hypnotherapy and 502 liter/min after one year. There was no charge in the FEV1/FVC and MMFR before and after therapy. School attendance and academic performance may be a helpful adjunct in asthma therapy during adolescence.

Adolescent↗

Lowering broken appointment rates at a teenage health center.

In an attempt to increase physician efficiency by lowering the "no show" rate of adolescents in a teenage health center, the possible variables related to broken appointments were explored. A new triage system was implemented. While most of the variables studied did not differ between the "show" and "no show" adolescents, there were significant differences based on the chief complaint. Those teenagers seen for well adolescent care had a 55% "no show" rate, those with noncosmetic problems had a 37% "no show" rate, and those with cosmetic complaints had a zero "no show" rate. With the implementation of a new triage system which required parent/adolescent involvement, the "no show" rate fell by 50%, thus dramatically decreasing the waiting time for initial appointment and improving the utilization of physician and nurse time.

Adolescent↗

Adolescent self-assessment of sexual maturation: reassessment and evaluation in a mixed ethnic urban population.

Pubertal changes correlate better with sexual maturity ratings than with chronological age. The applicability of sexual maturity ratings to research is impeded by the necessity to disrobe the adolescent. This study demonstrates that a mixed ethnic urban group of adolescent females can self-assess their own developmental stages by using standard photographs of sexual maturity stages. However, males do less well in self-assessment. Self-ratings by 22 female adolescents and 22 male adolescents aged 11 to 18 were compared to physicians' assessment. There was total agreement in 17/22 (r=0.87) breast stage assessment, 16/22 (r=0.86)female pubic hair assessment, 10/22 (r=0.72) male genital assessments and 11/22 (r=0.69) male pubic assessments. The mean differences in sexual maturity ratings between physician and adolescent were 0.32 for female pubic hair assessments, 0.64 for male pubic hair assessments, 0.68 for male genital assessments and 0.28 for breast assessments. This study suggests the feasibility of self-assessment of sexual maturity rating among black, white, and Hispanic adolescent females, but the need for further research before it is used among adolescent males.

Adolescent↗

Low prevalence of Chlamydia trachomatis in the oropharynx of adolescents.

This study determined the prevalence rates of Chlamydia trachomatis infection in the oropharynx of adolescents with and without pharyngitis. One hundred teenagers with and without symptoms of pharyngitis were cultured for C. trachomatis. Swabs were taken from the oropharynx and tonsillar areas for direct fluorescent antibody assay and cell culture. Of the 100 adolescents enrolled in the study 55% had a history of pharyngitis and 45% had no pharyngeal symptoms; 29% were male and 71% were female. The mean age was 15.5 years. Forty-two percent had a history of sexual intercourse, and 11.5% described a history of oral-genital sex. Only one 14-year-old female with a 2-week history of a sore throat had a positive culture. Her direct fluorescent antibody assay was inconclusive and the throat culture for Group A Streptococcus was negative. She had no history of sexual activity. The overall prevalence rate in the 100 adolescents was 1% with a 1.8% prevalence in the symptomatic group and 0 in the asymptomatic group. Of the symptomatic adolescents 39 had cultures for Group A Streptococcus and 8 (20.5%) were positive. The results of this study suggest that C. trachomatis is a rare inhabitant of the oropharynx in adolescents and is not a common cause of pharyngitis.

Adolescent↗