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Biomedical subjects

L S Matveeva

Publications and source records attributed to L S Matveeva.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Mechanisms of regulation of high cardiac output in patients with hypertension (angiocardiographic study)].

To identify mechanism conditioning high cardiac output, an angiocardiographic study was conducted in 39 patients with essential hypertension. Increased stroke and cardiac output was found to be due to increased venous inflow, with inotropic condition of the hypertrophic myocardium being reduced in spite of enhanced general pumping function of the left ventricle. As arterial hypertension tended to stabilize and cardiac output declined, total peripheral resistance assumed the principal responsibility for its regulation, whereas at earlier stages of the disease it shows either normal, or even reduced levels, and venous inflow is the principal factor controlling cardiac and stroke output.

Adult↗
PubMed1982

[Transcutaneous intravascular balloon dilatation in renal artery stenosis and arterial hypertension].

In 20 patients with stenosis of the renal artery and arterial hypertension Gruentzig balloon catheter was introduced transcutaneously into the artery with subsequent dilatation. In 2 cases arterial pressure became normal, in 8 the course of the disease improved, in 4 high hypertension was retained but responded to hypotensive agents, in 2 there was no effect, and in 4 balloon dilatation could not be carried out due to the impossibility of pushing the catheter through the stenosed segment of vessel. According to the data of renal scintigraphy plasma flow on the affected side rose by 16-66% after dilatation as compared to the initial figures, there was no significant change in the contralateral kidney.

Adult↗
PubMed1982

[Clinical and angiographic comparisons in stable stenocardia].

Comparative data of clinical, instrumental and coronarographic studies in 185 patients with ischaemic heart disease and stable angina pectoris are presented. It is concluded that in the evaluation of the severity of ischaemic heart disease along with the clinical data it behooves to give due consideration to the additional signs of chronic ischaemia of the myocardium: changes in repolarization on ECG at rest and after exercise, local disorders of the function of the left ventricle, disorders of lactic acid metabolism and cardiac rhythm.

Adult↗
PubMed1982

[Combined renal forms of symptomatic arterial hypertension].

In high arterial hypertension conditioned by main renal arteries stenosis of different genesis, 21.1% of patients were found to have a combination of renovascular hypertension with parenchymatous renal diseases, most often chronic pyelonephritis. The incidence of development of the malignant hypertension syndrome in combined lesions was noted to be 1.5 times higher than in isolated renovascular hypertension and makes 38.8% of patients. The described features of the clinical course, laboratory, radiological and radionuclide data as well as morphologic state of kidneys make it possible to distinguish this form of symptomatic hypertension as a special one, that is renovascular-parenchymatous hypertension.

Chronic Disease↗
PubMed1982

A long-term follow-up study of the arterial pressure dynamics after nephrectomy in patients with renal hypertension.

For periods of 3 to 15 years after unilateral nephrectomy the arterial pressure dynamics was studied in 131 patients. In 18 patients with and 12 patients without remission of hypertension the renal haemodynamics was studied before and after nephrectomy. The functional compensatory mechanisms of the remaining kidney are assessed on the basis of preoperative checkings of selective renal haemodynamics and of the activities of the renin-angiotensin and prostaglandin systems in 10 patients with absent and 15 patients with decreased excretory function of one kidney. In the authors' opinion, the blood flow in the contralateral kidney increases, at lacking excretory function of the other kidney, owing to enhanced prostaglandin A2 synthesis in the contralateral kidney.

Adolescent↗
PubMed1981

[Pulmonary hemodynamics and cardiac function in severe arterial hypertension].

The central and pulmonary hemodynamics and contractility of the cardiac ventricles were studied using catheterization and cine-angiocardiography in 11 patients with high arterial hypertension and 10 patients with no cardiovascular pathology. Pulmonary hypertension was not recorded in the patients with high arterial hypertension having no clinical symptoms of the heart failure. The pressure in the pulmonary circulation is determined only by the level of the left ventricular end-diastolic pressure, which is moderately elevated in the patients with arterial hypertension due to manifest myocardial hypertrophy. Higher pressure in the pulmonary circulation system in the patients with high arterial hypertension as compared with the control group is explained by the increased left ventricular rigidity due to compensatory hypertrophy. It was shown that diastolic pulmonary arterial pressure reflected left ventricular end-diastolic pressure with sufficient accuracy, exceeding it by an average 2.5 mm Hg. The functional interrelationship has been shown between the cardiac ventricles both in health and in high arterial hypertension.

Adult↗
PubMed1981

The peculiarities of lipid and protein components of the high- and low-density lipoproteins in patients suffering from coronary atherosclerosis with different number of affected coronary arteries.

In 81 patients with coronary atherosclerosis, with different number of affected coronary arteries determined by selective coronarography, the blood plasma levels of low-density (LDLP) and high-density (HDLP) lipoproteins were determined, and their lipid and protein components were analyzed. In patients with two and three arteries affected, there were found -- in comparison with the control group (patients with neurocirculatory asthenia) and patients with one coronary artery affected: higher total cholesterol, triglycerides, cholesterol of very-low-density lipoproteins (VLDLP), LDLP cholesterol, and moderate value of the VLDLP+LDLP cholesterol/HDLP cholesterol ratio(s.c. atherogenicity coefficient). The HDLP cholesterol level was decreased in all groups of patients with coronary atherosclerosis. Along with the increasing number of arteries affected the percentage of esterified cholesterol in the HDLP decreased, free cholesterol in the HDLP and esterified cholesterol in the LDLP rose.

Adult↗
PubMed1981

[Value of dipyridamole test in the diagnosis of ischemic heart disease].

The diagnostic test with dipyridamol was carried out in 83 patients with ischaemic heart disease (IHD) and cardialgias of various genesis, with diagnosis verified by coronarography and veloergometry. IHD patients after dipyridamol had angina pectoris attacks with or without ischaemic changes on ECG, which points to latent coronary insufficiency. The appearance of an anginal attack with the depression of the ST segment is typical of IHD with stenosing coronary atherosclerosis, as a rule, with developed collateral vessels. As to sensitivity and specificity in detecting IHD the dipyridamol test is equal to the bicycle ergometry tests. With the results of both tests considered the frequency rate of detection of IHD is increased. The dipyridamol test is recommended for diagnosis of IHD in therapeutic and cardiological hospitals.

Adult↗
PubMed1980

[Comparative study of carbohydrate metabolism in ischemic heart disease in the presence and absence of coronary atherosclerosis].

Eighty-nine males suffering from ischemic heart disease and 20 practically healthy males were examined. Coronarography demonstrated atherosclerotic changes in the coronary arteries of the heart in 79.8% of patients, 20.2% of patients had no such changes. Disorders of carbohydrate metabolism were revealed in 55% of patients. High incidence of carbohydrate metabolism disorders was found in patients with intact coronary arteries of the heart, which was close to that in the group of patients with ischemic heart disease and moderate coronary atherosclerosis (44%). The basal level of immunoreactive insulin (IRI) was significantly higher in patients with coronary atherosclerosis than in the controls, at the same time this increase was not significant in patients with intact coronary arteries. IRI reached peak level in patients with ischemic heart disease and atherosclerotic changes on the 20th minute of glucose or insulin load, and this level was higher than that in the controls. The rise in the IRI level on the 20th minute of glucose or insulin load was much less in patients with ischemic heart disease but without signs of coronary atherosclerosis than in patients who had atherosclerotic lesions in the coronary arteries of the heart.

Adult↗
PubMed1980

[Use of ultrasonic scanning of the kidneys and abdominal portion of the aorta in the diagnosis of certain forms of symptomatic arterial hypertension].

Ultrasonic scanning of the kidneys, abdominal aorta, and renal arteries was conducted in 2 patients with hypertensive disease and in 13 with symptomatic arterial hypertension. An ultrasonogram of a normal kidney and aorta was obtained, as well as ultrasonograms with changes recorded in pyelonephritis, polycystosis of the kidneys, atherosclerosis and panarteritis of the abdominal aorta and its branches. Ultrasonography is a noninvasive, informative method which does not harm the patient. It may be used in the diagnosis of some forms of symptomatic arterial hypertension associated with affection of the kidneys and abdominal aorta. Ultrasonic scanning is particularly valuable in the examination of patients for whom radiocontrast methods are contraindicated.

Adult↗