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Biomedical subjects

L S Geisler

Publications and source records attributed to L S Geisler.

At least 19 recordsLinked to original sources

[Effectiveness of proxyphylline in chronic obstructive pulmonary disease (author's transl)].

The bronchospasmolytic action of proxyphylline given intravenously in a dosage of 16 mg/kg body weight was assessed by spirometry and bodyplethysmography in 12 patients with chronic obstructive pulmonary disease. Proxyphylline serum levels were estimated in parallel repeatedly. In the majority of patients a bronchospasmolytic effect could be established (lowering of airway resistance by 30% in 9 and by 40% in 7 patients). In some an action was demonstrated for up to 4 hours. There were no serious side effects and in particular no adverse cardiovascular reactions or skeletal muscular tremor.

Adult