[Ventricular activation in the Wolff-Parkinson-White syndrome, type B. Vectorcardiographic studies].
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Biomedical subjects
Publications and source records attributed to L Russo.
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Thirty patients resuscitated from out-of-hospital cardiac arrest (15 with and 15 without postanoxic coma on admission) underwent a clinical examination and neuropsychological testing. In order to assess quality of life, they were compared to two matched control groups; 15 patients with previous myocardial infarction and 15 healthy subjects. None of the survivors showed severe neurologic impairment, and all had returned to self-sufficient physical activity. However, the behavior rating scale scores were significantly worse in patients with postanoxic coma. The processing ability linked to memory was significantly worse in the postanoxic coma group. Mood disorders were also observed in this group, but they did not have pathological significance. The remarkably low incidence of neurologic and psychological sequelae in these resuscitated patients, particularly in those with early clinical evidence of severe cerebral damage, is an encouraging result that supports the therapeutic systems development and efforts in the management of out-of-hospital cardiac arrest.
This study was designed to assess the effectiveness of early prehospital intravenous administration of lidocaine in preventing primary ventricular fibrillation (PVF) in patients with suspected acute myocardial infarction (AMI). Sixty patients with suspected AMI, seen by the Mobile Coronary Care Unit (MCCU) of Florence, were randomly allocated at home to treatment with lidocaine (bolus i.v. of 1 mg/kg, followed by an infusion of 4 mg/min) or placebo (infusion of saline at a rate of 1 mL/min), respectively. The lidocaine group (27 patients) and the control group (33 patients) were not significantly different in age, clinical condition, or time of randomization. The diagnosis of AMI was confirmed in all 60 patients during the hospital stay. Ventricular fibrillation (VF) occurred in 5 patients in the control group in comparison to none in the lidocaine group (P < 0.05). Three patients experienced VF at home and were successfully resuscitated by an MCCU cardiologist. In another two patients, VF occurred during the first 4 hours after onset of symptoms. No major side effects were observed after the infusion of lidocaine. Our findings support the effectiveness of the prophylactic administration of lidocaine in preventing PVF in the prehospital phase of AMI and suggest that the drug can be safely administered in this setting by prehospital personnel.
The causes of death among the dock-yard workers of Genoa from December 31, 1959 to January 1, 1970, have been investigated. These workers, mainly assigned to ship repair, refitting and construction, are exposed to several noxious substances, such as: asbestos, silica, paint solvents, welding smoke and volatile products of petroleum. Two different control groups were selected: the male population of Genoa and the staff of the San Martino Hospital in Genoa. Causes of death showing a significant increase were: gastric cancer (only in comparison with the hospital staff), cancer of colon excluding rectum, lung cancer, cancer of kidney, urinary bladder and other urinary organs, respiratory diseases, cirrhosis of the liver, cardiovascular diseases (only in comparison with the hospital staff).
In order to evaluate the phonatory results obtained with the use of tracheoesophageal prostheses, 38 laryngectomees were examined, 20 of which underwent erigmophonic voice rehabilitation while the other 18 were rehabilitated with the application of a prosthesis. In all cases electroglottography and spectrography of the voice were performed. In the erigmophonic-voice subjects, electroglottography gave a normal glottic wave while spectrography gave a tracing with frequent interruptions, scarce harmonics, altered by the presence of background noises. In the tracheoesophageal prosthesis patients, the electroglottogram showed regular hypopharynx vibratory activity while the spectrogram appeared free of interruptions activity while the spectrogram appeared free of interruptions and presented a uniform distributions and presented a uniform distribution of suffixes. The data obtained demonstrate that better results are obtained with the use of tracheoesophageal prosthesis as it allows the exhaled air to be used in phonation and thus respects respiratory dynamics and pneumophonic synergism. It also makes it possible to achieve a clear, fluent voice. Furthermore, the results obtained with patients with this prosthesis were constantly satisfactory when the long exercises required were performed.
This report described the case of a patient with cardiac rhabdomyomas and tuberous sclerosis (TS), associated with Down's syndrome. Diagnosis of TS was made subsequently to sebaceus adenomas, peri-ungual fibromas and ash leaf macules, mental retardation, epilepsy, renal and cerebral calcification findings. Physical examination, ECG and Holter ECG monitoring revealed normal cardiac findings. Two dimensional echocardiography disclosed the presence of two areas of increased acoustic density; one of which was at the level of postero-medial papillar muscle and the second appeared to be adherent to ventricular septum. Left ventricular size, function and intracavitary blood flow were normal.
Voluntary horizontal saccadic eye movements (SEM) were recorded in 148 drug free healthy subjects (15-75 years of age). None had history and/or objective evidences of CNS abnormalities. SEM recordings took place always at the same time of the day, after a standard lunch. Peak saccadic velocity (PSV), saccade latency (SL) and saccade accuracy (SA) were extracted for each saccade session. A negative linear correlation was found between SEM parameters (PSV, SA, SL) and age. Aged subjects showed a significant (p less than 0.01) elongation of the to locate the target, a significant (p less than 0.01) decrease in PSV and a significant (p less than 0.01) decrement in SA.
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On the ground of preceding researches carried out about myodystrophias, the authors studied the melituric symptomatology in both a group of myasthenic patients and a group of control. The chromatographic analysis and the dosage of some urinary carbohydrates, showed that there are not statistically significant differences between the group of myasthenic patients and that of controls.
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