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Biomedical subjects

L Romano

Publications and source records attributed to L Romano.

194 records · Page 11Linked to original sources
PubMedDate not supplied

Resistant ovary syndrome and fertility.

The authors report two cases of women with resistant ovary syndrome who were hospitalized because affected by secondary amenorrhoea. The development, in these women, of secondary sexual characteristics was normal. Neither x-ray of the sella turcica nor examination of the visual fields revealedany abnormalities. They had a normal female karyotype (46/XX). The plasmatic gonadotrophin levels, especially of FSH, were markedly raised. Administration of GnRH elicited strong responses in FSH and LH, corresponding to what is normally seen in post-menopausal women. The concentration of 17 beta-estradiol in the serum was low. The prolactin levels were normal. The patients were subjected to laparoscopy with ovarian biopsy. The ovaries were small but without morphological abnormalities. The hystological picture, similar in both ovaries, showed a cortical zone of normal appearance with an ordinary number of primordial follicles. Both patients received therapy by estrogens (epimestrol). After a period from three to seven months they showed normal ovulatory menstrual cycles. Now one of these women is pregnant.

Adult↗
PubMedDate not supplied

[A comparative multicenter study of the efficacy of single- and double-lumen catheter drainage].

Our study was aimed at comparing the therapeutic efficiency of single and double lumen catheters in the drainage of abdominal fluid collections. We report the results of in vitro and in vivo studies carried out to assess the usefulness of each catheter type based on its therapeutic results. In the in vitro study the aspiration efficacy of the catheters was tested in a simulated cavity. In the in vivo study 188 patients with 206 fluid collections in the abdomen were examined; the patients had been treated percutaneously with single or double lumen catheters, randomly. In each patient we studied drainage efficiency related to aspiration efficacy, the time the catheter rested in the cavity, patient's discomfort and finally the cost of both the device and hospitalization. Some patients underwent surgery for specific reasons, but nevertheless their clinical conditions were absolutely improved thanks to percutaneous drainage. The results of this study yield useful clinical data to choose the most suitable catheter for the percutaneous treatment of abdominal fluid collections. Single lumen catheters work better than double lumen ones, the latter being also more expensive. Hospitalization time is also reduced when single lumen catheters are used.

Adolescent↗
PubMedDate not supplied

Hepatitis type C: modes of transmission and preventive measures.

There is general agreement that the hepatitis C virus is efficiently transmitted parenterally, while data on viral transmission from mothers to babies or by sexual or non-sexual household contact are conflicting. In Italy, hepatitis C accounts for approximately 20% of all cases of acute viral hepatitis. It is more frequent among young persons (15-24 years old), among those living in the southern part of the country or on the islands, and in males than in females (3:1). In recent years the incidence rate has dropped and significant changes in the HCV transmission patterns have been observed. As a consequence of the implementation of anti-HCV screening and the introduction of increasing restrictions on donor eligibility, the proportion of cases arising from blood and blood component transfusions has significantly declined. A candidate vaccine to protect against hepatitis C virus is now under development.

Adolescent↗
PubMedDate not supplied

[Diagnostic approach to acute laryngeal trauma: role of computerized tomography].

Aim of this study was to assess the role of Computed Tomography (CT) in the management of acute laryngeal injuries by reviewing our 5 years' experience. From January, 1991, to November, 1996, sixteen patients with blunt trauma and 2 patients with penetrating injuries of the larynx underwent physical examination, laryngoscopy and CT; 2 of them underwent angiography too. The patients were divided into 3 groups according to Schaefer classification [13], first on the basis of physical examination, CT and laryngoscopy findings. The definitive group and therapy were decided on the basis of final spatial assessment. Physical examination diagnosed the presence and the anatomical level of laryngeal injuries in group I (4 patients); laryngoscopy and CT depicted the type of injury and suggested conservative management in 100% of cases. In group II (10 patients), conservative management was suggested by CT findings in the laryngeal, submucosal soft tissues and fascial plane injuries in 100% of cases. Physical examination findings were correct in 30% of cases, questionable in 30% and incorrect in 30%; the exam was not performed in 10% of cases. Finally, laryngoscopy findings were correct in 60% of cases, incorrect in 20% and not diagnostic in 20%. In group III (2 patients), exposed laryngeal injuries required immediate surgery. In group II, the selective application of CT was useful for assessing the degree of damage in 100% of cases and was helpful in planning conservative management. CT avoided surgery in one patient, showed laryngeal cartilaginous features in 2 patients and 2 pseudoaneurysmal injuries not suspected on the basis of physical examination findings.

Adolescent↗