Biomedical subjects
L Roberts
Publications and source records attributed to L Roberts.
Low-rate smokers.
BACKGROUND: Some smokers maintain a low daily smoking rate and do not appear to be addicted to nicotine (tobacco "chippers"). In a context of increasing social and environmental constraints on cigarette smoking, it is of interest to determine the population prevalence and the characteristics of low-rate smoking behavior. METHODS: A representative population survey was used to determine the prevalence and the correlates of low-rate smoking (five or less cigarettes a day). A range of sociodemographic, contextual, cognitive, and smoking-behavior variables was examined. RESULTS: Of 697 smokers age 20 years and over who had smoked for more than 2 years, 8.2% smoked five or less cigarettes a day; their average age was 39 years, and half were under 35 years of age; 88% had been smoking for 6 or more years; 86% were in the contemplation or preparation stages of readiness to quit. The significant independent predictors of being a low-rate smoker, compared to smoking at a higher daily rate, were perceiving quitting as not very difficult, smoking the first cigarette of the day more than 30 min after walking, buying packets of 30 or less cigarettes, and having not been advised by a doctor to quit. CONCLUSIONS: There were few differences between low-rate and other smokers on the range of variables that we were able to assess in a population survey. Since there is no safe level of cigarette smoking, medical advice to quit and public-education campaigns could target low-rate smokers specifically. Such initiatives could make significant contributions to reducing overall smoking prevalence.
Can we target smoking groups more effectively? A study of male and female heavy smokers.
BACKGROUND: In recent years a number of studies have examined subgroups within the smoking population. These studies have provided information which facilitate improved targeting of programs and interventions to help smokers quit. Despite this there have been few population studies which have described male and female heavy smokers and compared their characteristics. METHODS: We used representative population data on 789 smokers to examine differences between light and heavy smokers of each gender and between male and female heavy smokers directly. RESULTS: Of those who smoked, 35% of males and 24% of females were classified as heavy smokers and represent a large target group within the smoking population. Whereas a light smoker was characterized as smoking a median of 12.5 cigarettes per day, the heavy smoker smoked a median of 32 cigarettes per day. Univariate comparison of heavy smokers and light smokers showed a number of statistically significant differences according to demographics, in smoking behaviors and knowledge, in beliefs about smoking, in smoking characteristics, and in other health indicators. Because of interactions between gender and work/leisure day smoking variation, separate logistic regression models based on gender were fitted to the data. Again, compared with light smokers, several significant differences emerged for both heavy female and heavy male smokers under the headings mentioned above. Further logistic regression analyses showed differences between male and female heavy smokers when compared directly. CONCLUSIONS: The smoking population of South Australia is not homogeneous and this segmentation study has shown the need for varying approaches to different segments when developing intervention programs.
Smoking-related beliefs and behaviour among adults with asthma in a representative population sample.
BACKGROUND: Smoking and exposure to environmental tobacco smoke are inadvisable for adults with asthma. AIMS: To determine the smoking prevalence and daily smoking rate of asthmatics and compare smoking-related beliefs and behaviours among smokers with and without asthma. To compare beliefs of asthmatics about passive smoking and asthma, how many are exposed at home and what they do when they are exposed, with people who do not have asthma. METHODS: A representative population survey of 3019 South Australian adults aged 15 years and older interviewed in their own homes in late 1992. RESULTS: Twenty-eight per cent of asthmatics were smokers; mean daily smoking rate was 17.6. Asthmatics had similar patterns of smoking, readiness to quit and quit attempt histories as people without asthma. More than 40% of smokers with asthma did not perceive that smoking had greatly affected their health, over half did not believe they were at risk in future and two-thirds did not think future health problems would be serious. Among non-smokers, despite being more convinced of the effects of passive smoking on asthma, and being more concerned about exposure, those with asthma were no more likely to take protective action in response to actual or imminent exposure than those without asthma. One in ten non-smokers with asthma were exposed to smoking at home. CONCLUSIONS: The smoking habits of adults with asthma are cause for concern, with many asthmatic smokers perceiving they are not personally at risk from their smoking. Health education principles should be used by health professionals caring for asthmatic smokers to guide the selection and delivery of smoking cessation strategies. Prevailing restrictions on indoor smoking play an important role in protecting the respiratory health of non-smokers with asthma.
Smoking-related beliefs and behaviour of South Australians with diabetes.
Data cumulated from three representative population surveys (n = 9402) in South Australia were used to determine smoking prevalence of those aged 15 years or over with and without self-reported medically confirmed diabetes. Overall, smoking prevalence in the two groups did not differ. However, among those aged under 40 years with self-reported diabetes, smoking prevalence approached 55 per cent, which was significantly higher than in young respondents without diabetes (32 per cent). Diabetic smokers were no more likely than were nondiabetic smokers to have tried to quit or to be ready to quit; one-quarter of diabetic smokers had no thought of quitting or of modifying their habit. Smokers with diabetes were significantly more likely to be heavy smokers (43.5 per cent) than were nondiabetic smokers (23.4 per cent). Fewer smokers with diabetes tended to believe that smoking causes or aggravates heart disease or circulatory problems than did other smokers, although these differences did not reach statistical significance. Additional effort is required to find methods to assist people with diabetes to refrain from smoking.
Photoelectron core-level spectroscopy and scanning-tunneling-microscopy study of the sulfur-treated GaAs(100) surface.
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Serological evidence implicating Neospora species as a cause of abortion in British cattle.
By means of an immunofluorescence antibody test (IFAT), using in vitro cultured parasites as antigen, antibodies to Neospora species at titres > or = 1/1280 were found in 11 of 120 Scottish cattle that had recently aborted but in only one of 97 cattle from herds in which there had been no recent abortions (P < 0.01). The specificity of the antibodies was confirmed by the lack of cross reactivity between samples with high titres to Neospora and toxoplasma antigen in a direct agglutination test, and by the absence of reactivity at > or = 1/640 in the IFAT of convalescent sera from cattle infected experimentally with Toxoplasma gondii, Sarcocystis cruzi, Eimeria bovis, E alabamensis, Cryptosporidium parvum and Babesia divergens. These results demonstrate that Neospora species infection occurs commonly in aborting cattle in Britain, and that the IFAT may be a useful tool for investigating the infection.
Leroy Hood: thinking big in Seattle.
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Haptoglobin as an indicator of infection in sheep.
An automated method for the estimation of the acute phase protein haptoglobin was developed and used to compare the blood haptoglobin concentrations of 42 sheep examined post mortem with other haematological findings in infectious and non-infectious conditions. Haptoglobin was also assayed in 863 sheep from nine apparently normal flocks; of these sheep seven per cent had significantly raised haptoglobin levels. The studies showed that haptoglobin was useful as a marker for the presence of bacterial infection in sheep, and was more sensitive, specific and efficient and less likely to give false positive and negative results than a haematological examination.
P300 differences between non-alcoholic young men at average and above-average risk for alcoholism: effects of distraction and task modality.
1. P300 event-related electroencephalographic potentials were recorded from 79 young adult males, cross-classified with respect to the presence/absence of a family history of alcoholism (FHA) and the presence/absence of a personal history of antisocial personality (ASP) disorder. P300s were elicited using visual and auditory oddball tasks. Each oddball task was repeated with a tracking task added as a distractor. 2. In general, distraction increased the latencies and reduced the amplitudes of P300s elicited by the oddball stimuli. The P300 latency increase occurred only in low risk ASP- and FHA- groups. There was no adaptive increase in P300 latency in the higher risk ASP+ and FHA+ groups. 3. Group differences in P300 were restricted to visual tasks. No interpretable group differences in P300 latency or amplitude were found during the auditory tasks.
Evaluation of Clearview Chlamydia.
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Survival following intentional massive overdose of 'Ecstasy'.
A case of intentional overdose with 18 'Ecstasy' tablets is described. 'Ecstasy' is a semi-synthetic hallucinogenic amphetamine and acute adverse reactions follow from the effects of sympathetic stimulation. To our knowledge this is the first reported case of massive intentional overdose reported in the literature.
Single fibre EMG studies in chronic fatigue syndrome: a reappraisal.
Single fibre EMG studies were carried out on the right extensor digitorum communis muscle in 30 subjects with chronic fatigue syndrome and in 30 age and sex matched controls. Abnormal jitter was seen in five patients with chronic fatigue syndrome. Slight but significant differences between the mean consecutive differences in the remainder of the chronic fatigue subjects and the control subjects were recorded. Overall the differences were so minor that it seems unlikely that a disturbance of neuromuscular function as reflected by jitter measurement has a pathogenetic role. It is suggested that the increased jitter seen may be explained by the effects of the variability of motor unit firing rates on the myogenic component of the jitter.
Prolonged pregnancy: two years experience of offering women conservative management.
A prospective study of 199 patients over a two year period, 1 Jun 90 to 31 May 92 at the Louise Margaret Maternity Wing, Cambridge Military Hospital, Aldershot was undertaken to audit the uptake of an offer of conservative management of prolonged pregnancy to women at 42 weeks gestation. The labour outcomes of patients opting for conservative or induction management plans were recorded and the increased workload introduced to the Ultrasound Unit measured. Of the 91/199 (45.7%) patients who chose to be managed conservatively, 20 (22.0%) developed an abnormal result of a test of fetal surveillance, 16 (17.6%) were electively delivered because of an abnormal result. There were no significant differences in labour performance or neonatal outcome between those women opting for conservative management or induction of labour. 201 new ultrasound scans were booked, 129 were performed (0.4 scans/week/1000 deliveries).
NIH, DOE battle for custody of DNA sequence data.
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A thin lifeline to genome researchers.
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Zeroing in on a breast cancer susceptibility gene.
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The AO classification of long bone fractures: an early study of its use in clinical practice.
Over a period of 6 months, 543 long bone fractures were classified using the AO classification system. Factors important in determining the management of fractures occurring in three regions; hip, forearm and tibia, were identified. In hip fractures, we found that the anatomical configuration of the fracture, and therefore its classification, generally determined management. However, there were other factors that influenced the more specific form of surgical treatment used. In forearm fractures, the age of the patient was the most important factor determining treatment, while many factors, including consultant preference, determined the treatment of tibial fractures. While we found the system useful for audit purposes, we also found that it was unnecessarily complicated and often fell short of playing a useful role in the planning of management.