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Biomedical subjects

L Robert

Publications and source records attributed to L Robert.

At least 397 records · Page 22Linked to original sources
PubMedDate not supplied

[Problems of the prenatal prophylaxis of the viral infections (author's transl)].

The present review will supply an simple notice over the characters of every one viral infection interesting the materne-faetal conditions, and also propose the most convenient intervention for each observed type. A not small lot of these problems are not resolved in the field of the antiviral immunity regarding the mother and newborn.

Cytomegalovirus Infections↗
PubMedDate not supplied

Modification of fibronectin distribution pattern in solid human tumours.

Using indirect immunofluorescence, the distribution pattern of fibronectin has been studied in a variety of solid human tumours and corresponding normal tissues. Fibronectin could be detected on normal epithelial cell membranes, in periglandular and perivascular basement membranes and in the intercellular stroma. No modification of this distribution pattern was detected in a variety of benign tumours or in certain pathological, non-malignant disorders (Dupuytren's contracture). In infiltrating mammary carcinomas, cell membrane staining disappeared even before invasion, the staining pattern of the glandular basement membranes became patchy, discontinuous and finally disappeared with invasion. Fibronectin persisted on vascular basement membranes and in the fibrous matrix remaining between the areas of infiltration. Similar modified fibronectin patterns were observed in bronchial, endometrial, prostatic, urinary bladder and thyroid carcinomas. In sarcomas, fibronectin disappeared from the membranes of transformed cells and decreased in intensity in the intercellular matrix. It can be stated, therefore, that the progressive loss of cell membrane and glandular basement membrane bound fibronectin is a characteristic feature of malignant human tumours and may assist with the histological differential diagnosis of atypical lesions and early invasion.

Basement Membrane↗
PubMedDate not supplied

[Cerebrospinal fluid immunoglobulins in various types of meningitis].

The Authors using new immunochemical method studied the increases of CSF fluid immunoglobulin fractions during bacterial, viral and tuberculous meningitis. IgG, IgM and IgA levels are increases in all forms of acute meningitis, therefore the rise result most marked in bacterial. It presents further increase in the later stages of viral meningitis. The Authors valued, by mathematical proceeding, IgG, IgA and IgM variations to offer further physiopathologic, diagnostic, therapeutic and prognostic aknowledgements.

Adolescent↗