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Biomedical subjects

L Revol

Publications and source records attributed to L Revol.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

[Treatment of 100 acute myeloid leukemias (author's transl)].

Between november 1974 and august 1976, 100 acute myeloïd leukemias were treated by the same protocol L. 275. Induction treatment was daunorubicine, vincristine, cytosine arabinoside, in one intensive course for patients under 65 and cyclophosphamide (CPM), VCR and CAR in a less intensive and repetitive courses for patients over 65. In remission, there were three phases: consolidation, prevention of central nervous system leukemia, maintenance. All patients in remission received an androgenotherapy and two groups were randomised: chemotherapy and chemotherapy plus BCG. 68 patients were in complet remission (CR) 61 out of 80 patients under 65 and 7 out of 20 over 65. Median duration of first remission was 12 months. Median duration of survival was 13 months for all patients, 15 months for patients under 65, 3 months for patients over 65, and 22 months for 68 patients in CR. Survival of patients receiving BCG was slightly better than patients without BCG.

Adolescent↗
PubMedDate not supplied

Delayed hypersensitivity skin reactions in the induction phase of remission in acute non lymphoid leukemias.

Delayed skin reactions to Tuberculin (10 units, intradermal) and Candidin (1:1000, intra dermal) were studies in a homogenous group of 41 patients with acute non lymphoid leukemias in their initial phase. Remission-rate is higher in non-anergic patients (63%) than in anergic patients (32%), (p less than 0.05). Death-rate (within 30 days after chemotherapy) is higher in anergic patients (50%) than in non-anergic patients (16%), (p less than 0.05). There is no correlation between delayed skin reactions and age, initial absolute counts of neutrophil-lymphocyte-monocyte-blast cells, and results of humoral immunity. Delayed skin reactions are interesting in defining a high-risk group in the induction phase of remission of acute non lymphoid leukemias.

Acute Disease↗