Development of glutamine synthetase activity in chick embryo retina cultures in the absence of added hydrocortisone.
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Biomedical subjects
Publications and source records attributed to L Reif-Lehrer.
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Hydrocortisone has been found to induce glutamine synthetase activity in chick-embryo retinas in culture. Evidence is presented to show that the hydrocortisone is definitely required for transcription; its requirement for translation has not been ruled out. The possible identity of hydrocortisone with an active component of calf-serum diffusate reported earlier is discussed. The data also indicate that the glutamine synthetase messenger RNA is stable for at least several hours.
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