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Biomedical subjects

L Radermacher

Publications and source records attributed to L Radermacher.

7 recordsLinked to original sources
PubMed1992

[Renal functional reserve].

The concept of renal functional reserve (RFR) was introduced in the 80's. The renal functional reserve was defined as the ability of the kidney to increase Renal Plasma Flow (RPF) and Glomerular Filtration Rate (GFR) after a stimulus as a protein load. The absence of RFR defines a state of hyperfiltration which seems to be a detrimental factor for the progression of renal failure. The measure of RFR by a protein load test is thus a mean to detect glomerular hyperfiltration and allows to give adequate diet prescription.

Atrial Natriuretic Factor↗
PubMedDate not supplied

[Metabolic emergencies related to diabetes mellitus: ketoacidosis and hyperosmolar state].

Diabetic ketoacidosis and hyperglycaemic hyperosmolar state are relatively frequent metabolic emergencies. Such entities complicate type 1 and type 2 diabetes mellitus, respectively. Diagnosis is ultimately provided by blood and urine analysis. The pathophysiology is mainly based on insulin privation regarding ketoacidosis and resistance to insulin in hyperglycaemic crisis, with an additional deleterious role of counterregulatory hormones. Prognosis of such complications remains generally severe. Management is based on insulin infusion, fluid resuscitation as well as concomitant compensation for electrolytes losses.

Diabetes Mellitus, Type 1↗