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Biomedical subjects

L Röhl

Publications and source records attributed to L Röhl.

At least 37 records · Page 2Linked to original sources

[Treatment of ureteral obstruction and urinary fistulas after kidney transplantation].

In 285 renal transplantations, performed during the years 1967-1978, 6 ureteral obstructions (2,1%) and 15 urinary fistulas (5,3%) were observed. Ureteral obstructions occurred in the late phase after transplantation and were caused by strictures at the uretero-vesical anastomosis (two patients), compression of the ureter by enlarged kidney during rejection (one patient) resp. lymphocele (one patient) and strictures at the pyelo-ureteral junction (two patients). Satisfactory results were achieved by surgical treatment in all patients. Urinary fistulas occurred in the early postoperative phase. Two vesical, 12 vesico-ureteral and one calyceal fistula were observed. 7 fistulas (1 vesical, 6 vesico-ureteral) closed spontaneously after temporary drainage of the bladder. 8 fistulas were repaired surgically. While satisfactory results were obtained in 13 patients, two patients died due to infection and sepsis after reoccurrence of fistulas.

Drainage↗

Alloplastic replacement of the canine ureter by expanded polytetrafluoroethylene (gore-tex) grafts. Preliminary report.

In 12 female dogs, subtotal unilateral (8 dogs) or bilateral (4 dogs) ureteric resection and replacement by expanded polytetrafluoroethylene (Gore-Tex) prostheses were performed. Follow-up consisted of periodic excretory urographies. Short- and long-term results, consisting of periodic excretory urographies for up to 12 months, are promising and induce further studies with this new type of graft.

Animals↗

Long-term results in children following dialysis and renal transplantation.

Since 1966, 93 children in end-stage renal disease, aged between 5 and 16 years were treated by a combined programme of dialysis and transplantation. In 91 patients treatment of uraemia was started either as hospital or home haemodialysis, until now covering more than 90 dialysis years. Forty-one children were transplanted. Twenty children died during dialysis treatment, 7 after renal transplantation. Sixty-six children are currently alive, 25 with a functioning graft, 28 are treated by hospital dialysis, 13 by home haemodialysis. Eighty-three per cent of the patients on hospital dialysis are classified in rehabilitation category 2 according to the EDTA categories, and all children on home dialysis and those with functioning grafts, category 1.

Adolescent↗

The use of double renal transplants from paediatric cadaver donors.

In 224 consecutive kidney transplantations, 3 patients, aged 44, 37 and 13 years received double renal transplants from paediatric cadaver donors aged 1 day, 23 and 19 months respectively. Both adult recipients developed severe hypertension during postoperative rejection crises leading to multiple graft ruptures in the recipient of the neonatal kidneys. 1 patient died from massive gastrointestinal bleeding 4 weeks after transplantation while kidney function was satisfactory. Excellent graft function was achieved in the 3rd patient. The techniques of removal, preservation and transplantation of double renal transplants are described. The significance of increasing the potential number of donor kidneys by the use of paediatric cadaver donors is stressed.

Adolescent↗

Prune belly syndrome: treatment of terminal renal failure by hemodialysis and renal transplantation.

The second case of successful renal transplantation in a patient with "prune belly" syndrome is reported. In spite of early aggressive surgical approach in the management of this disease terminal renal failure frequently ensues. Hemodialysis and renal transplantation have offered new possibilities of prolonging life in these patients. The success of renal transplantation depends on the anatomic and functional state of the lower urinary tract. Pretransplant urologic examination is extremely important for the evaluation of urinary tract abnormalities.

Abdominal Muscles↗

An experimental model for extracorporeal renal surgery: ex situ removal of artificially induced renal staghorn calculi in ambiothermia.

An experimental model for the evaluation of surgical techniques and preservation in extracorporeal surgery is described: staghorn calculi were induced in 15 dogs by the injection of methylmethacrylate into the renal pelvis. Removal of the calculi was carried out 3-4 weeks later on a workbench, using microsurgical techniques and ex situ radiographies. 15 min of warm ischaemic and 6 h of ambiothermic preservation were well tolerated as could be demonstrated by determination of the serum creatinine following autotransplantation and immediate contralateral nephrectomy.

Animals↗

Simultaneous cine-urographic and manoflowmetric evaluation of the neurogenic component in incontinence.

For diagnosis of incontinence the exact analysis of the dynamics of micturition is of great importance, primarily in order to evaluate the urethral flow-resistance and detrusor activity. Extending already existing methods for the evaluation of urodynamics, we developed a complex method of cine/pressure/flow/cystourethrography. All data were recorded and simultaneously stored on videotape. Especially in cases of incontinence with a neurogenic component important information for a causative therapy was gained using this complex investigation. Thus in 20 patients with incontinence, studied for exclusion of a neurogenic component, we found two patients with a neurogenic bladder dysfunction that had been unknown prior to the examination. The neurogenic component in each case had remained unnoticed by usual routine diagnostic procedures.

Humans↗

Urological complications in renal transplantation.

The urological complications associated with 128 consecutive renal transplants performed in the Department of Urology of the University Hospital Heidelberg between February 1967 and January 1975 are described. Extravesical ureteroneocystostomy has shown to be the preferable method for urinary tract reconstruction, providing satisfactory results in our hands. The technique of ureteroneocystostomy at the dome of the bladder, performed since 1967 in our series, is described and its advantages discussed. There was an overall incidence of urological complications of 21.2%. Major urological complications occurred in 18 patients (14.1%), urinary fistulae in 11 patients (8.6%), ureteric obstruction in 4 patients (3.2%) and spontaneous parenchymal ruptures in 3 patients (2.3%). Only two grafts were lost, due to spontaneous parenchymal ruptures. The mortality directly due to major urological complications was 5.6%. Minor complications (hydrocele, epididymitis, urethral stricture, urinary calculi) were seen in 9 patients (7%). Lymphoceles were not encountered. The management and outcome of urological complications are described.

Adolescent↗