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Biomedical subjects

L R Weekes

Publications and source records attributed to L R Weekes.

At least 19 recordsLinked to original sources
PubMed1986

Burkitt's lymphoma of the ovaries.

A case of Burkitt's lymphoma involving both ovaries of a 15-year-old Guatemalan girl is presented along with a brief review of the pertinent literature.

Adolescent↗
PubMed1985

Disseminated intravascular coagulation.

Disseminated intravascular coagulation (DIC) is not uncommon in the obstetric patient, but DIC of sufficient severity to be of clinical importance is unusual. Treatment of DIC is directed primarily at its cause. Replacement of depleted blood components with packed red blood cells, fresh frozen plasma, cryoprecipitate, and platelets is sometimes required for treating hemorrhage. Heparin should be used only rarely, and only to help control life-threatening hemorrhage because DIC is refractory to vigorous and adequate blood-component therapy. With careful planning of treatment, adherence to a few general principles, and the combined approach of an obstetrician and a coagulationest, fatalities and major morbidity should be rare.

Abruptio Placentae↗
PubMed1984

Ruptured spleen as a differential diagnosis in ruptured tubal pregnancy.

Two cases of traumatic biphasic or secondary splenic rupture are presented to demonstrate the clinical picture of an entity the obstetrician-gynecologist will be encountering more commonly in the future. The signs and symptoms of this condition figured prominently in the differential diagnosis of ruptured tubal pregnancy.

Adult↗
PubMed1983

The role of the obstetrician-gynecologist in the management of breast lesions.

This paper is based on the author's frequent experience in the diagnosis of breast masses in his everyday practice as an obstetriciangynecologist. It appears that gynecologists, by the very nature of their practices, are in an excellent position to head the case-finding expedition for breast lesions. Furthermore, the obstetrician-gynecologist can use acquired surgical skills to great advantage in the management of benign lesions and assist surgical associates in the management of the malignant lesions.

Adenofibroma↗
PubMed1983

Cesarean section: a seven-year study.

This paper reports a seven-year study of cesarean section practices at the Queen of Angels Hospital, Los Angeles, California. Indications for this procedure are listed in detail and an attempt is made to explain its increasing frequency. Practicing physicians were interviewed and testimony seemed to indicate, as was suspected, that fear of malpractice suits was one of the reasons for cesarean section. The conventional wisdom of "once a section always a section" is questioned with regard to an increasing number of trials of labor and vaginal deliveries, when they are considered feasible and safe. The federal government is manifesting serious interest in this increased number of operative deliveries in the light of cost effectiveness.

Breech Presentation↗
PubMed1981

Carcinoma of the ovary.

The data for this paper are based on 50 patients discharged from the Queen of Angels Hospital with a diagnosis of carcinoma of the ovary from 1972 to 1978.Currently, ovarian cancer is the leading cause of death of all pelvic malignancies. Peak incidence of ovarian cancer is found in women between 40 to 65 years of age. Symptomatology includes often vague abdominal discomfort, dyspepsia, and other digestive disorders which may be present for several months prior to diagnosis.The workup for suspected ovarian cancer should include a careful history, physical examination, pelvic, and rectal examinations, Pap smear, CBC, urinalysis, SMA 12 (blood chemistries), chest x-ray, and intravenous pyelography as indicated. Sonography, lymphangiography are optional.Traditionally, operative treatment has been the keystone of management for ovarian carcinoma. In view of the unsatisfactory results with operation and radiotherapy in disseminated disease, chemotherapy has been used widely. Hope for the future lies in further development of immunodiagnosis and immunotherapy.

Adult↗
PubMed1980

Renal shutdown as a complication of severe preeclampsia with premature separation of the placenta.

The author, with long experience in the management of toxemia of pregnancy and its multiple complications, is reporting his first case of complete renal shutdown after severe preeclampsia complicated by premature separation of the placenta, and complications of disseminated intravascular coagulopathy.Multiple hemodialyses provided a breakthrough to what appears to be a complete reversal and return of normal renal function.

Acute Kidney Injury↗
PubMed1979

Five year study of postpartum hemorrhage: Queens of Angels Hospital, 1973--1977.

Postpartum hemorrhage accounts for about one quarter of the deaths in the obstetric hemorrhage group. Blood loss is the most important underlying cause of morbidity. To save blood, the obstetrician must partice "preventive medicine" by being cognizant of any situation during pregnancy, labor and delivery which may result in increased blood loss.The methods and principles by which these situations can be prevented or treated are discussed.

Adult↗
PubMed1977

Surgical complications of gynecologic surgery.

Complications of gynecological surgery are considerable and when reviewed in detail are almost frightening. There is no substitute for experience and intimate knowledge of the intricate pelvic structures in health and disease.Anyone who is active in the field is sooner or later going to experience some difficulty whether it be due to his miscalculation or to innate conditions in the patient which are beyond his/her control.It is the responsibility of the pelvic surgeon to recognize the complication and apply proper corrective measures. The patient should not be given false hopes of sure success nor should she be deprived of whatever hope for success does exist.

Abortion, Spontaneous↗
PubMed1977

Massive fibroid.

This ten-year study of the massive fibroid at the Queen of Angels Hospital will reveal an average of 66 cases per year which could be classified as large and massive. Only about ten cases per year qualify as massive (four gestational months or larger). There were none considered giant size (25 lbs or more).The literature is replete with these, one of which (weighing 100.2 lbs) will be reported in detail. The mortality rate continues to be considerable in these (14.8 to 16.7 percent). In the smaller tumors, mortality is rare and morbidity is minimal.Bleeding, pain, and pressure symptoms, due to impingement on neighboring organs, are the principal symptoms. Sarcomatous change, fortunately, still remains quite rare.Treatment usually involves a pre-operative dilatation and curettage when bleeding is a problem, followed by total abdominal hysterectomy and bilateral salpingo-oophorectomy where indicated. Appendectomy is usually incidental. Anesthesia is usually spinal, if not otherwise contraindicated.Ultrasound is a new and refined diagnostic tool.

Female↗