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L R Kirkland

Publications and source records attributed to L R Kirkland.

At least 19 recordsLinked to original sources

Role models.

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Career Choice

Ocular sensitivity to thimerosal: a problem with hepatitis B vaccine?

Strict interpretation of the package insert for hepatitis B vaccine (Heptavax-B and Recombivax HB) would preclude its administration to anyone with a history of ocular sensitivity to thimerosal, but data to support this are hard to find. Given the large number of vaccinees, many of whom wear contact lenses, reported cases of significant adverse reactions are sparse. No studies have directly addressed the ocular sensitivity issue. For two years, we monitored an immunization program for hospital employees. Ten employees (2.2%) gave a history of ocular sensitivity to thimerosal. Nine were vaccinated, without untoward reactions. This small series does not resolve the safety issue and should not be so interpreted. Likewise, the question of danger remains unanswered. If others administering the vaccine would ask the proper questions, sufficient numbers could be generated and reported that would either support the contraindication, or lead to a change in its present wording.

Drug Hypersensitivity

Condom leakage.

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Equipment Failure

Optimum energy for performing CT iodinated constrast studies.

A study has been made of CT contrast for iodine as a function of X-ray energy from 80 to 140 kV constant potential. The EMI CT 1010 scanner was used for phantom measurements of contrast signal, noise, artefact and dose. The results show that optimum detectability occurs at 80-100 kV, with the close efficiency being somewhat better at 80kV.

Models, Structural