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Biomedical subjects

L R Jarvis

Publications and source records attributed to L R Jarvis.

22 records · Page 2Linked to original sources
PubMed1983

The cellular response to human colonic neoplasms: macrophage numbers.

Tumour cells and macrophages are thought to interact and the behaviour of tumours may be modified by macrophage activity. Using an immuno-histochemical method for the demonstration of lysozyme and a computerised image analysis system, the number of macrophages was assessed in and around tubulovillous adenomas and the different Dukes grades of adenocarcinomas of the colon. No significant differences were demonstrated and it is concluded that the behaviour of these neoplasms is not related to the number of associated macrophages.

Adenocarcinoma↗
PubMed1981

Microdensitometry with image analyser video scanners.

A numerical method for calibration of the Quantimet 720 1D Auto detector as a densitometer in absolute density units has been developed and applied to integrated microdensitometric measurement. A procedure for the estimation and correction of microscope glare error has also been derived. The error after glare correction was found to be comparable with threshold setting variation encountered in routine use of the Quantimet. The method should prove valuable in densitometric applications not only for Quantimet image analysers but also for any instrument employing a video imaging system because the underlying principles are the same.

Densitometry↗
PubMed1980

Effect of nicotine on the morphology of the rat gastric mucosa.

The effect of oral nicotine dosage on the morphology of the rat gastric mucosa was studied. Cell populations, neck cell mucus volume fraction, and mucosal area and depth were measured, and differences in mean values for each group were tested for statistical significance. It was found that the equivalent of approximately 10 times the normal daily intake of nicotine achieved by human smoking is related to a significant decrease in total mucus neck cell population, neck cell mucus volume fraction and mucosal depth and to an increase in mucosal surface area. The nicotine doses caused no significant changes in the parietal or chief cell populations, body weight, or water consumption.

Animals↗