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Biomedical subjects

L R Eversole

Publications and source records attributed to L R Eversole.

At least 91 records · Page 5Linked to original sources

Psychometric profiles and facial pain.

The myofacial pain-dysfunction syndrome and atypical facial pain are the most prevalent chronic pain disorders of the facial region. Previously, the myofacial pain-dysfunction syndrome included all TMJ/masticatory muscle pain, jaw dysfunction, and joint clicking. We have segregated two major subgroups subsumed within this diagnostic classification and have assigned them to a myogenic facial pain (MFP) group and a TMJ internal derangement (TMJID) group. Significant age and personality differences were uncovered when these subpopulations were compared to subjects with atypical facial pain (AFP). Both MFP and TMJID groups are relatively homologous, involving younger persons than AFP subjects. Alternatively, when MFP, TMJID, and AFP subjects were compared for differences in MMPI psychometric scales, MFP and AFP subjects exhibited significantly higher scores, particularly for hypochondriasis, depression, and hysteria, than did TMJID subjects. It is concluded that subcategorization of myofascial pain-dysfunction patients into a myogenic pain group and a TMJ internal derangement group is justified on the basis of psychometric differences. Furthermore, psychopathologic factors are more significant among MFP and AFP subjects than among TMJID patients.

Adult↗

Cystic ameloblastoma. A clinicopathologic analysis.

Thirty-three cases of ameloblastoma arising from odontogenic cyst linings are presented. Lesions of this nature have been referred to as "unicystic ameloblastoma." Our data support the findings of others in that this lesion differs from the solid invasive varieties of ameloblastoma, as the former occurs in a younger age group and exhibits a low rate of recurrence following enucleation or curettage. On the basis of histopathologic features we provide evidence that these lesions represent mural and luminal ameloblastomatous change in a pre-existing cyst rather than cystic degeneration of a solid tumor.

Adult↗

Dental occlusal wear and degenerative disease of the temporomandibular joint: a correlational study utilizing skeletal material from a contemporary population.

Forty crania and mandibles with intact dentition exceeding twenty-six teeth and bilaterally intact condyle-fossa apparatus were evaluated for attrition and degenerative joint disease. The skeletal specimens all represent a twentieth-century contemporary American population from the Atkinson Skull Collection at the University of the Pacific School of Dentistry. While 23.1% of this sample exhibited some degree of erosive osseous degenerative wear involving the condyle or articular fossa and 76.3% exhibited occlusal tooth wear, no significant correlation between the degree of attrition and the severity of degenerative joint disease could be documented.

Adult↗

Clear cell odontogenic tumor: histochemical and ultrastructural features.

Clear cell odontogenic tumor, a rare epithelial jaw lesion of putative odontogenic origin, histologically resembles clear cell adenocarcinomas. Ultrastructural and histochemical features are described and support a non-glandular derivation. The intraosseous neoplasm is characterized by ovoid nests of clear or finely stippled cells with a mature collagenous stroma. These cells are PAS-positive, diastase labile and fail to bind alcian blue. Enzyme histochemical reactions disclose dehydrogenase, non-specific esterase, and acid phosphatase positivity. Fine structural characteristics include plasma membrane microvilli, desmosomes, endoplasmic reticulum, free ribosomes, glycogen rosettes and lysosomes. Many cells exhibit a paucity of cytoplasmic organelles with prominent vacuolization. Centrioles and annulate lamellae are also encountered. Summarily, clinical, radiographic, histochemical and ultrastructural features indicate that this neoplasm is probably of epithelial odontogenic origin with cytodifferentiation emulating glycogen-rich presecretory ameloblasts.

Adenocarcinoma↗

The role of dental restorative metals in the pathogenesis of oral lichen planus.

Twenty-four subjects with oral lichen planus and twelve control subjects without oral mucosal disease were patch tested with dental restorative metals and selected metallic salts. Twenty-one percent of the lichen planus population exhibited a positive skin response to one or more challenge materials, as compared to 8% of the control population. It is concluded that oral lichen planus subjects show a higher correlation with delayed hypersensitivity to dental metals than a control population; however, a cause-and-effect relationship cannot be substantiated.

Adult↗

Radiographic characteristics of cystogenic ameloblastoma.

Radiographic patterns encountered in mandibular cystogenic ameloblastoma, a variant encountered among teen-agers and young adults, are described and correlated with age and recurrence after surgery. More than 75% of the cases are located in the posterior mandibular ramus area, and 50% are associated with an impacted third molar. The predominant radiographic patterns include unilocular and scalloped or macromultilocular pericoronal , interradicular , or periapical expansile radiolucencies.

Adolescent↗

Focal sclerosing osteomyelitis/focal periapical osteopetrosis: radiographic patterns.

Forty-one histologically documented instances of focal sclerosing osteomyelitis and focal periapical osteopetrosis have been evaluated for radiomorphologic characteristics. These reactive lesions exhibit five distinct patterns that include periapical focal opacifications, target lesions, radiolucencies, multiconfluent configurations, and opacifications with concomitant root resorption. While an irritational origin can usually be detected in chronic sclerosing osteomyelitis, the cause of focal periapical osteopetrosis remains enigmatic.

Chronic Disease↗

Focal acantholytic dyskeratosis of the oral mucosa.

Focal acantholytic dyskeratosis represents a clinically heterogeneous group of dermatologic and mucosal lesions which share common histologic features. Oral mucosal variants of this condition are extremely uncommon. Two intraoral cases are presented, of which one depicts a solitary nodular pattern (warty dyskeratoma) and the other represents a papular lesion exhibiting multiple acantholytic foci.

Acantholysis↗

Oral and gingival changes in systemic sclerosis (scleroderma).

Nineteen patients with systemic sclerosis, including two with CREST syndrome variant, were clinically evaluated for oral and gingival manifestations of their disease. Subjectively over 50% complained of xerostomia, limited opening, recurrent "mouth sores" and dysphagia. Four patients indicated that they had been refused dental care due to limited accessibility to the oral cavity. Objectively, physical examination disclosed prominent lingual and buccal mucosal crenations and loss of tongue mobility with fibrotic induration in 25% of the subjects examined. Three of the patients with advanced disease exhibited foci of severe gingival recession due to fibrous strictures and attached gingiva stripping. None of the patients showed any indication of uncontrolled dental disease secondary to xerostomia.

Adult↗

Oral Kaposi's sarcoma associated with acquired immunodeficiency syndrome among homosexual males.

Clinical disease states encountered in the acquired immunodeficiency syndrome (AIDS) have been reviewed with an emphasis on oral Kaposi's sarcoma. The disease is reaching epidemic proportions among homosexual males and is characterized by onset of fever, malaise, diarrhea, and lymphadenopathy. Subsequent to these initial nonspecific signs and symptoms, patients develop a variety of opportunistic infections or Kaposi's sarcoma (or both). The oral lesions of Kaposi's sarcoma are characterized by red, blue, or purple plaques or nodules encountered primarily, yet not exclusively on the palate. Other oral manifestations of AIDS include candidiasis and herpetic stomatitis. Epidemiologic studies suggest the probability of a transmissible agent, perhaps a virus. It is recommended that dental care should be rendered to these patients, using mask and gloves with autoclave sterilization of all instruments.

Acquired Immunodeficiency Syndrome↗

Intraoral and labial keratoacanthoma.

Keratoacanthoma (KA) is a relatively common skin lesion of questionable histogenic origin. Although cutaneous KAs are considered to arise from hair follicles, the rare cases reported occurring on mucous membranes would suggest possible origin from surface epithelium. A review of the literature revealed six previous cases involving oral mucosa. Seven new cases of keratoacanthoma are presented. Four occurred on the lower lip, and three arose from intraoral mucosal tissue, accounting for a total of nine reported intraoral cases.

Adult↗

Effects of suspected foodstuff challenging agents in the etiology of recurrent aphthous stomatitis.

Two hundred eighteen professional students were surveyed to uncover any association of recurrent aphthous stomatitis (RAS) with a history of allergic diathesis. No significant relationship was uncovered. From this population approximately equal numbers of RAS-positive and RAS-negative subjects were challenged with suspected foodstuff agents thought to have a potential causative role in occurrence of the disease. The results failed to document any causative effect with regard to tomatoes, strawberries, or walnuts.

Adult↗