Pedal papule. Eccrine porocarcinoma (EPC) in association with poroma.
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Acrospiroma↗
Biomedical subjects
L R Bigler
Publications and source records attributed to L R Bigler.
Painful ulcers of the scrotum. Pyoderma gangrenosum (PG).
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Adult↗
Uterine adenocarcinoma metastatic to the skin responsive to megestrol acetate.
BACKGROUND: Although endometrial carcinoma is the most common gynecological cancer, it only rarely metastasizes to the skin, with a reported prevalence of 0.8%. We report a case of an elderly lady who recently developed cutaneous metastases from an endometrial primary diagnosed 7 years earlier. OBJECTIVE: Our purpose was to determine if the oral administration of megestrol acetate would be effective in the treatment of uterine adenocarcinoma metastatic to the skin. METHODS: The index case was given oral megestrol acetate over a period of 9 months. Pre- and posttreatment skin biopsies were performed and analyzed. RESULTS: During treatment with megestrol acetate, the cutaneous metastases in the abdominal skin decreased in area to less than 10% of the pretreatment surface area correlating with a marked histopathologic decrease in adenocarcinomatous glandular structures. CONCLUSION: Megestrol acetate can be successfully utilized in the treatment of endometrial adenocarcinoma metastatic to the skin as well as ostensibly in the treatment of other progesterone-sensitive metastatic cutaneous carcinomas.
Adenocarcinoma↗
Religiosity and locus of control of adolescent cancer patients.
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Adaptation, Psychological↗