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Biomedical subjects

L Piana

Publications and source records attributed to L Piana.

At least 73 records · Page 4Linked to original sources
PubMed1985

[Radiation and surgical treatment of cancer of the cervix uteri in proximal stages I and II].

No results from therapeutic trials describing the best therapeutic procedure for cervical carcinoma in stages I and IIa are available. Analysis of a series of 242 cases of cervical carcinoma in stages I and IIa, from 1975 to 1980, treated with radical surgery and radiation therapy, yields a therapeutic approach that envisions the most reliable evaluation of subclinical extension, cure of cervical tumor and prevention of pelvic or extra-pelvic metastases with a minimum of post-radiation problems. The choice of combination surgery and radiation therapy is primarily determined by staging and the volume of the central pelvic tumor. For stages I and IIb (upper third of vagina involved) with central pelvic tumor less than 4 cm in diameter, the usual procedure is recommended i.e. radium application, total hysterectomy with pelvic lymphadenectomy followed by external irradiation of pelvic lymphatics in cases with lymphadenopathy. For stages IIb (obvious parametrial involvement) and for stages I or II with central pelvic tumor between 4 and 6 cm in diameter: total dose external and internal pelvic radiation therapy followed by total hysterectomy without pelvic lymphadenectomy but with exploration of obturator, hypogastric, external iliac, common iliac, and aortic nodes. For the rare supravaginal central pelvic tumors greater than 6 cm in diameter, the risk of clinical evaluative error and incomplete sterility by irradiation alone, warrants first an explorative laparotomy using Wertheim's procedure, then pelvic lymphadenectomy and exploration of pelvic and aortic lymph nodes.

Adult↗
PubMed1981

[Carcinoembryonic antigen (C.E.A.). Its value in the care of malignant tumours of the ovary (author's transl)].

The authors report on 466 serial levels of carcinoembryonic antigens (C.E.A.) carried out with the aim of surveying 44 patients who had malignant tumours of the ovaries : - one third of the cases had a positive level more than 10 ng per ml; - the presence and the serial level depend more on the histological nature of the tumour than the stage of its evolution; - when a serial level has been negative before treatment it has never become positive in in a definite and continuous manner when the tumour progresses. On the other hand, when the test is positive before any therapy is started then there is a good correlation between its clinical evolution, its response to treatment and the serial variations. Relying on their experience and on the results given in the literature, the authors suggest a scheme of practical use of levels of C.E.A. in the care of malignant tumours of the ovary.

Carcinoembryonic Antigen↗
PubMed1979

[The value of tomodensitometry in the treatment of carcinoma of the uterus (author's transl)].

The authors performed pelvic and lumbo-aortic tomodensitometry (TDM) in 67 patients with invasive carcinoma of the cervix. Localisation of the cervix is aided by the insertion of a vaginal marker and by opacification of the bladder and rectum. The density and appearance of tumour tissue are identical to those of normal uterine muscle. Under such conditions, TDM is of no use in seeing partial or total involvement of the cervix without any increase in cervical size. TDM gives a clear picture of hypertrophic neoplastic cervices and may be used to obtain exact measurements. TDM offers valuable information in cases of spread to the parametrium, lymphadenopathy or visceral metastases. During radium therapy, TDM shows the relationships between the radioactive sources and the centri-pelvic tumour. It facilitates the drawing of isodose curves. TDM is not a method suitable for the early diagnosis of carcinoma of the cervix. It adds very useful complementary information to clinical examination and classical investigation.

Female↗
PubMed1977

[Hormone receptors in fibroadenomas of the breast].

This study is about hormone receptivity carried out on 84 fibroadenomata of the breast. In displaying the intracellular receptors for oestradiol and progesterone it shows that hormone receptivity was maximum in benign conditions as they were starting in young women with a short clinical history and with most marked cellular density on anatomo-pathological examination. We compare our results with those that were obtained in cases of cancer of the breast and show in parallel the plasma steroid levels that were obtained in women with benign pathological conditions of the breast.

Adenofibroma↗