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Biomedical subjects

L Persky

Publications and source records attributed to L Persky.

At least 73 records · Page 4Linked to original sources

Synergistic gangrene of the scrotum and penis secondary to colorectal disease.

We recently encountered 5 patients with synergistic gangrene of the genitalia secondary to colorectal disease. This number of cases suggests that there may be an increasing incidence of this entity that has been reported only several times in the past. Pseudomonas was one of the organisms cultured in all cases. Because of the high mortality rate we advocate aggressive therapy, consisting of early and repeated radical débridement into normal tissues and appropriate management of the colorectal source of contamination. Our experience indicates that the lower gastrointestinal tract should be considered as a possible cause of infection in all cases of synergistic gangrene of the scrotum and penis.

Colonic Diseases↗

Microsurgical anastomosis of vas deferens: an experimental study in the rat.

A patency rate of more than 90 per cent was achieved after 52 vasovasostomies. Satisfactory results were shown in both internally stented and nonstented anastomoses. A higher incidence of foreign body reaction was associated with silk sutures. Sperm granulomas and reduced patency were noted when superficial sutures were used indicating that a leakproof anastomosis is essential.

Animals↗

A comparison of the healing processes in uremic and parallel-fed rats.

The effect of nutrition on the healing capacity of uremic rats was investigated. Wound tensile strenth and the amount of collagen formation in polyvinyl sponges implanted subcutaneously were compared in a group of uremic rats and a group of nonuremic rats parallel-fed an identical diet and caloric intake. Wound tensile strength in the parafed rats closely and significantly approximated that in the uremic snimals conpared to the stronger wounds in the controls. A correlation was also noted for collagen accumulation in the uremic and parafed groups. This experiment lends further evidence to support the theory that the mechanism of action for the shown poor healing associated with uremia is based on the poor state of nutrition in the uremic animal.

Animal Nutritional Physiological Phenomena↗

Epidemiology of cancer of the penis.

World-wide incidences of penile cancer are reviewed and epidemiologic factors including ciecumcision, hygiene, phimosis, smegma, irritation, infection, veneral disease, viruses, environment, race, immune response, trauma, and age are discussed. The lowest rates appear in groups practicing infant circumcision and in areas where standards of sexual hygiene are high.

Africa↗

Is cystectomy a safe procedure in elderly patients with carcinoma of the bladder?

Often total cystectomy is not advocated in elderly patients for the treatment of carcinoma of the bladder. A group of 25 patients more than 70 years old were reviewed to determine if cystectomy is a reasonable therapeutic alternative in elderly individuals. Since there was satisfactory survival and no immediate operative mortalities elderly patients should not be denied this form of therapy on the basis of age alone. A higher incidence of postoperative complications was noted in the patients treated previously with radiation therapy.

Aged↗

Complications of autonomic dysreflexia.

Autonomic dysreflexia can be a life-threatening problem if not promptly recognized and treated. Since the most common cause is bladder distension it is essential that the urologist be familiar with this syndrome. Several patients with serious complications owing to autonomic dysreflexia, including 1 mortality, are presented. The complications of autonomic dysreflexia result from a sudden marked rise in blood pressure, which may be severe enough to rupture single or multiple cerebral blood vessels or lead to a considerable increase in intracranial pressure. The neurophysiology, clinical features and therapeutic measures are discussed.

Adolescent↗

Initial complications and late results in dismembered pyeloplasty.

A total of 109 dismembered pyeloplasties has been reviewed and examples of initial complications and their management are discussed. These early complications do not preclude excellent long-term results. Over-all followup studies show resolution of pain, hematuria and infection in the vast majority of patients. X-ray results have since, in general, improved or stabilized. No nephrectomies have been done subsequent to the repair of the hydronephrosis.

Adolescent↗

The changing clinicopathological pattern of abscesses in or adjacent to the kidney.

We reviewed retrospectively 43 patients with various renal and perirenal abscesses. In contrast to previously published data a primary renal etiology was noted for nearly every abscess in or adjacent to the kidney, irrespective of the type of abscess. Currently, the concept that the renal carbuncle is a metastatic abscess whose origin lies at some distant site may be applicable no longer. Despite earlier recognition of symptoms, improved diagnostic techniques and better therapy the morbidity and mortality of abscesses in and adjacent to the kidney remain high, suggesting the important role of associated medical conditions and the need for early aggressive therapy.

Abscess↗

Post-traumatic priapism.

Review of 7 cases of post-traumatic priapism indicated that, despite the type of initial therapy, all patients expressed dissatisfaction with the total efforts, although erections were resumed. A surgical effort directed at drainage of fluid collections and correction of the ruptured tunic seems warranted and may aid the patients in further sexual activities.

Adult↗

Complications of Marshall-Marchetti-Krantz urethropexy.

The course of 2 patients with ureteral obstructions created during the Marshall-Marchetti-Krantz procedure is described. The superior or most craniad stitches of the repair were placed inadvertently through the bladder wall obstructing the ureterovesical junction on each side. Awareness of the possibility of this complication should aid in avoiding this mishap.

Female↗