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Biomedical subjects

L Pauling

Publications and source records attributed to L Pauling.

At least 109 records · Page 6Linked to original sources
PubMed1974

Are recommended daily allowances for vitamin C adequate?

The Recommended Dietary Allowance of vitamin C (ascorbic acid) for adults has now been set at 45 mg day(-1) by the U.S. Food and Nutrition Board. This intake suffices to prevent scurvy in most people. It is, however, much less than the optimum intake, the intake that leads to the best of health. A larger intake decreases the incidence and severity of the common cold and other diseases. Ascorbic acid has antiviral and antibacterial activity and is required for phagocytic activity of leukocytes. Several arguments indicate that for different human beings the optimum intake lies between 250 mg day(-1) and a much higher value, 5000 mg day(-1) or more. It is proposed that the present Recommended Dietary Allowance of 45 mg day(-1) of vitamin C for adults be renamed the Minimum Dietary Allowance, defined as the amount needed to prevent scurvy, and that, after consideration of the evidence about intake and the best of health, there be formulated another category of values, the Recommended Daily Intake, with the suggested range of 250 mg day(-1) to 4000 mg day(-1) of ascorbic acid for an adult.

Ascorbic Acid↗
PubMed1974

Resonance between a Prolate and a Superprolate Structure of the Er Nucleus.

Observed energy levels of (162)Er from the normal state J = 0 to the excited rotational state J = 18 correspond to values of the moment of inertia and rotational frequency that indicate that a pronounced change in structure occurs at about J = 14. It is shown that the observed values agree well with the values calculated on the assumption that there is resonance between a more stable prolate structure with a core of two spherons and a less stable superprolate structure with a core of three spherons in line.

Journal Article↗
PubMed1971

Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography.

When a human being is placed for several days on a completely defined diet, consisting almost entirely of small molecules that are absorbed from the stomach into the blood, intestinal flora disappear because of lack of nutrition. By this technique, the composition of body fluids can be made constant (standard deviation about 10%) after a few days, permitting significant quantitative analyses to be performed. A method of temperature-programmed gas-liquid partition chromatography has been developed for this purpose. It permits the quantitative determination of about 250 substances in a sample of breath, and of about 280 substances in a sample of urine vapor. The technique should be useful in the application of the principles of orthomolecular medicine.

Air↗
PubMed1971

The significance of the evidence about ascorbic acid and the common cold.

Only four independent double-blind studies have been reported of the effect of ascorbic acid regularly ingested in daily amounts more than 100 mg, in comparison with a placebo, in decreasing the incidence and integrated morbidity of the common cold for subjects exposed to cold viruses in the ordinary way and without colds when the test period began. A statistical analysis of these four studies leads to rejection of the null hypothesis that ascorbic acid has no more protective power than the placebo at the 99.86% level of confidence for the incidence of colds and the 99.9978% level of confidence for the integrated morbidity.

Administration, Oral↗
PubMed1970

Albert Tyler.

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Bibliographies as Topic↗